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A 3-hour infusion of cefiderocol in hospitalized paediatric patients is well tolerated and demonstrates activity against clinically relevant Gram-negative species of bacterial infections, reports a phase II study.

Cefiderocol safe to use in hospitalized children with bacterial infection

Pandemic babies have a 46 percent higher risk of atopic diseases

The incidence of atopic diseases in infants born in Hong Kong has increased by 46 percent during the COVID-19 pandemic, potentially linked to altered neonatal microbiome diversity resulting from vigorous disinfection. SIM03 and SIM05, symbiotic formulae developed with the aid of artificial intelligence (AI), are shown to improve eczema severity and quality of life (QoL) in children and adults, respectively, by modulating gut microbiota.

Pandemic babies have a 46 percent higher risk of atopic diseases

05 Feb 2025

Age, ventilation impact extubation outcomes in preemies

The likelihood of extubation failure in preterm neonates is high among those with lower gestational and chronological age and higher levels of pre-extubation ventilation support, according to the results of a systematic review and meta-analysis.

Age, ventilation impact extubation outcomes in preemies

$Infrequent zoledronate infusions prevent vertebral fractures in early postmenopausal women$

Infrequent zoledronate infusions prevent vertebral fractures in early postmenopausal women

In early postmenopausal women, intravenous infusions of zoledronate once every 5 years could help reduce the risk of vertebral fractures, according to a recent study.

Infrequent zoledronate infusions prevent vertebral fractures in early postmenopausal women

SC infliximab biosimilar boosts healing along all bowel segments under colonoscopy in CD

The efficacy of maintenance with a modified biosimilar of infliximab in promoting healing of inflamed mucosa in CD is observed across all SES-CD segments, a post hoc analysis of the LIBERTY-CD trial has shown

SC infliximab biosimilar boosts healing along all bowel segments under colonoscopy in CD

$Oral noninferior to IV antibiotics for fracture-related infections$

Oral noninferior to IV antibiotics for fracture-related infections

In the treatment of fracture-related infections, outcomes appear to be comparable when using oral vs intravenous (IV) antibiotics, according to a study.

Oral noninferior to IV antibiotics for fracture-related infections

Decades of daily incense use may culminate in limb-threatening condition

04 Feb 2025 bởi

Burning incense in the home every day for decades appears to have deleterious consequences, with a Singapore study linking this practice to a heightened risk of chronic limb-threatening ischaemia (CLTI), the most severe form of peripheral arterial disease (PAD).

Decades of daily incense use may culminate in limb-threatening condition

Allergy history, chemotherapy linked to oxaliplatin hypersensitivity reactions

In patients with colorectal cancer, a history of allergy, previous oxaliplatin exposure, and chemotherapy regimens appear to increase the risk of having oxaliplatin hypersensitivity reactions, results of a recent study have shown.

Allergy history, chemotherapy linked to oxaliplatin hypersensitivity reactions

Higher MCFAs tied to lower diabetes risk

04 Feb 2025 bởi

Dietary medium-chain fatty acids (MCFAs) are inversely associated with the risk of developing type 2 diabetes mellitus (T2DM), reports a study, noting a possible interaction between genetic susceptibility and circulating octanoic acid in moderating diabetes risk.

Higher MCFAs tied to lower diabetes risk

04 Feb 2025

Age, high-risk conditions predict RSV hospitalization in children

Hospitalization due to respiratory syncytial virus (RSV) infection in infants and children is significantly associated with younger age, high-risk conditions, and palivizumab-indicated underlying conditions, according to a study in Japan.

Age, high-risk conditions predict RSV hospitalization in children