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Buprenorphine extends antisuicide effect of ketamine in MDD

The use of buprenorphine helps prolong the antisuicidal benefits derived from treatment with ketamine in patients with major depressive disorder (MDD), suggests a study.

Buprenorphine extends antisuicide effect of ketamine in MDD

Mới đây

SCB holds slight edge over PCB for PAD in SIRONA trial

2 giờ trước bởi

The 3-year results from the SIRONA trial demonstrate the superiority of a sirolimus-coated balloon (SCB) over a paclitaxel-coated balloon (PCB) in terms of freedom from clinically driven target lesion revascularization (TLR) in patients with symptomatic femoropopliteal artery disease.

SCB holds slight edge over PCB for PAD in SIRONA trial

2 giờ trước

Novel GLP-1 RA for weight management clears phase 2 study

6 giờ trước

The investigational oral small-molecule glucagon-like peptide-1 receptor agonist (GLP-1 RA) elecoglipron yields meaningful weight reductions with a safety profile consistent with the drug class, according to a phase 2 dose-ranging study.

Novel GLP-1 RA for weight management clears phase 2 study

6 giờ trước

PCV15 prevents AOM occurrence in children

10 giờ trước bởi

The V114-032 trial, presented at ESPID 2026, finds that administering the 15-valent pneumococcal conjugate vaccine (PCV15) reduces the incidence of first vaccine-type acute otitis media (VT-AOM) among healthy children.

PCV15 prevents AOM occurrence in children

10 giờ trước

Topical chlorhexidine 1% reduces maternal, neonatal bacterial colonization

18 giờ trước

Topical application of chlorhexidine 1% proves effective at reducing bacterial load in both mothers and neonates, according to the results of a randomized controlled trial.

Topical chlorhexidine 1% reduces maternal, neonatal bacterial colonization

18 giờ trước

Oral probiotic supplementation may lower risk of preterm delivery recurrence

22 giờ trước bởi

Oral supplementation with probiotics containing Clostridium species may protect against the recurrence of spontaneous preterm delivery in high-risk pregnant women, according to a prospective, single-arm, trial conducted in Japan.

Oral probiotic supplementation may lower risk of preterm delivery recurrence

22 giờ trước

Opioid systems influence ketamine’s antidepressant effect

23 giờ trước

Complex interactions between glutamatergic, opioidergic, and GABAergic systems modulate the antidepressant effects of ketamine on cerebral blood flow (CBF) in patients with major depressive disorder (MDD), suggests a recent study.

Opioid systems influence ketamine’s antidepressant effect

23 giờ trước

Letermovir safe to use for CMV prevention in paediatric HSCT recipients

một ngày trước bởi

Real-life use of letermovir in paediatric recipients of haematopoietic stem cell transplant (HSCT) is generally safe and prevents the development of cytomegalovirus (CMV) disease, as shown in a study presented at ESPID 2026.

Letermovir safe to use for CMV prevention in paediatric HSCT recipients

một ngày trước

Lithium, antidepressant prevent relapse after ECT in patients with MDD

một ngày trước

A recent Delphi-based expert consensus has released guidelines on preventing relapse after a successful electroconvulsive therapy (ECT) for patients with major depressive disorder (MDD).

Lithium, antidepressant prevent relapse after ECT in patients with MDD

một ngày trước

Novel petrelintide shows promise in obesity treatment

một ngày trước bởi

Treatment with a once-weekly injectable petrelintide, a novel human amylin analogue, yields up to 10.7 percent weight loss through week 42 in adults with obesity or overweight, according to the phase II ZUPREME-1 trial presented at ADA 2026.

Novel petrelintide shows promise in obesity treatment

một ngày trước

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Buprenorphine extends antisuicide effect of ketamine in MDD

Buprenorphine extends antisuicide effect of ketamine in MDD

SCB holds slight edge over PCB for PAD in SIRONA trial

SCB holds slight edge over PCB for PAD in SIRONA trial

Novel GLP-1 RA for weight management clears phase 2 study

Novel GLP-1 RA for weight management clears phase 2 study

PCV15 prevents AOM occurrence in children

PCV15 prevents AOM occurrence in children

Topical chlorhexidine 1% reduces maternal, neonatal bacterial colonization

Topical chlorhexidine 1% reduces maternal, neonatal bacterial colonization

Oral probiotic supplementation may lower risk of preterm delivery recurrence

Oral probiotic supplementation may lower risk of preterm delivery recurrence

Opioid systems influence ketamine’s antidepressant effect

Opioid systems influence ketamine’s antidepressant effect

Letermovir safe to use for CMV prevention in paediatric HSCT recipients

Letermovir safe to use for CMV prevention in paediatric HSCT recipients

Lithium, antidepressant prevent relapse after ECT in patients with MDD

Lithium, antidepressant prevent relapse after ECT in patients with MDD

Novel petrelintide shows promise in obesity treatment

Novel petrelintide shows promise in obesity treatment