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Darolutamide + ADT, without docetaxel, shows efficacy benefits in mHSPC
Darolutamide plus androgen-deprivation therapy (ADT), without docetaxel, improves radiological progression-free survival (rPFS) and secondary efficacy outcomes vs placebo plus ADT in patients with metastatic hormone-sensitive prostate cancer (mHSPC), according to results of the global phase III ARANOTE trial presented at ESMO 2024.
Darolutamide + ADT, without docetaxel, shows efficacy benefits in mHSPC
07 Oct 2024
Aspirin may improve survival in PIK3CA-mutated colon cancer
Adjuvant treatment with aspirin appears to provide some protection in patients with resected, PIK3CA-mutant stage II and III colon cancer, demonstrating a clinically significant improvement (43 percent) in disease-free survival (DFS), suggests a study presented at ESMO Congress 2024.
Aspirin may improve survival in PIK3CA-mutated colon cancer
06 Oct 2024
Depression plus social isolation double down on work productivity
Depressive symptoms in working adults can erode workplace performance, with a sharper decline in productivity seen when depression co-occurs with social isolation, according to a study.
Depression plus social isolation double down on work productivity
05 Oct 2024
Pulmonary arterial hypertension outcomes better with early therapy augmentation with selexipag
In the treatment of patients with pulmonary arterial hypertension, adding selexipag as a third medication sooner rather than later is crucial to help prevent hospitalization and disease progression, as suggested in an emulated target trial.