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Adjuvant nivolumab delivers in muscle-invasive bladder cancer
Adjuvant nivolumab appears to improve survival outcomes in patients with muscle-invasive bladder cancer (MIBC) who have undergone radical surgery, regardless of prior exposure to neoadjuvant chemotherapy, according to additional data from the phase III CheckMate 274 trial.
Adjuvant nivolumab delivers in muscle-invasive bladder cancer
09 Mar 2025
Survival in mCRPC prolonged with talazoparib–enzalutamide combo
The combination of the PARP inhibitor talazoparib plus the androgen receptor-pathway inhibitor enzalutamide yields a clinically meaningful increase in the overall survival of patients with metastatic castration-resistant prostate cancer (mCRPC) being treated in the first-line setting when compared with enzalutamide alone, according to final data from the phase III TALAPRO-2 trial.
Survival in mCRPC prolonged with talazoparib–enzalutamide combo
08 Mar 2025
Does using GLP-1 RAs induce suicide in T2D patients?
Patients with type 2 diabetes (T2D) who use glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) appear to have no increased risk of suicidality when compared with the use of dipeptidyl peptidase-4 inhibitors (DPP-4is) or sodium-glucose cotransporter-2 inhibitors (SGLT-2is), a study has found.