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Patients with left-sided resectable pancreatic cancer (RPC) enjoy improved overall survival (OS) with neoadjuvant therapy compared with upfront surgery, a recent study has shown.

Neoadjuvant therapy extends survival in left-sided resectable pancreatic cancer

Poor infant sleep quality a red flag for autism

Findings from a population-based Australian study suggest that poor infant sleep quality is associated with more pronounced autism characteristics and increased odds of an autism diagnosis.

Poor infant sleep quality a red flag for autism

Novel agent lowers LDL-C in ASCVD at-risk patients

Inhibition of angiopoietin-like 3 (ANGPTL-3) with SHR-1918 leads to further low-density lipoprotein cholesterol (LDL-C) reductions in patients at increased risk of atherosclerotic cardiovascular disease (ASCVD), a phase II study has shown.

Novel agent lowers LDL-C in ASCVD at-risk patients

Temocillin a good alternative to carbapenems for bacteraemia

The use of temocillin demonstrates comparable efficacy and safety to carbapenems for the targeted treatment of bacteraemia due to third-generation cephalosporin-resistant Enterobacterales (3GCR-E), primarily from urinary sources, reports a study.

Temocillin a good alternative to carbapenems for bacteraemia

5-day antibiotic use viable in CAP patients with clinical stability

Antibiotic treatment may be done for 5 days, as opposed to at least 7 days, in hospitalized patients with community-acquired pneumonia (CAP) who had achieved clinical stability by day 3 to 5, suggests a study presented at ESCMID Global 2025.

5-day antibiotic use viable in CAP patients with clinical stability

16 May 2025

Updated EPIC-HR data bolster nirmatrelvir/ritonavir role against COVID-19

Updated data from the EPIC-HR* trial show reduced duration of COVID-19 symptoms and utilization of healthcare resources with nirmatrelvir/ritonavir (NMV/r) in high-risk, unvaccinated, nonhospitalized, symptomatic adults with COVID-19.

Updated EPIC-HR data bolster nirmatrelvir/ritonavir role against COVID-19

16 May 2025

Extended caffeine treatment for apnoea in preemies offers little benefit

Continuation of caffeine treatment for apnoea in moderately preterm infants does not help shorten hospitalization, according to a study.

Extended caffeine treatment for apnoea in preemies offers little benefit

Linaclotide improves bowel symptoms in children with functional constipation

Treatment with linaclotide led to significantly improved symptoms of incomplete bowel evacuation and straining in paediatric patients aged 6–17 years with functional constipation, according to a phase III study presented at DDW 2025.

Linaclotide improves bowel symptoms in children with functional constipation