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Adding the first-in-class selective glucocorticoid receptor antagonist relacorilant to nab-paclitaxel results in improved survival outcomes for patients with platinum-resistant ovarian cancer, as shown in the topline results of the phase III ROSELLA study.

Platinum-resistant ovarian cancer gets survival boost with add-on relacorilant

Symptoms for ARIs in children vary across age groups

Acute respiratory infections (ARIs) are associated with various symptoms across different age groups, according to a Korea study.

Symptoms for ARIs in children vary across age groups

Add-on olanzapine prevents RT-induced nausea, vomiting

In patients undergoing abdominal-pelvic radiation therapy (RT), treatment with olanzapine along with an antiemetic medication leads to a substantial decrease in RT-induced nausea and vomiting (RINV), with no serious adverse effects, reports a study presented at ASCO 2025.

Add-on olanzapine prevents RT-induced nausea, vomiting

01 Jul 2025

Surgery helps allay fear, worry in patients with thyroid cancer

Fear and worry significantly decrease among patients with low-risk thyroid cancer (TC) following surgery, reports a recent study.

Surgery helps allay fear, worry in patients with thyroid cancer

Can diet drinks help with weight management?

Replacing diet beverages with water over 18 months leads to greater weight loss, improved glycaemic control, and higher diabetes remission in women with type 2 diabetes (T2D) and overweight or obesity. The benefits were sustained throughout the 18-month trial.

Can diet drinks help with weight management?

01 Jul 2025

Aumolertinib shows promise in untreated EGFR-variant metastatic NSCLC

High-dose aumolertinib appears to provide progression-free survival (PFS) benefit to patients with untreated EGFR-variant non–small cell lung cancer (NSCLC) and brain metastases, while having a manageable safety profile, according to the results of a single-arm phase II study.

Aumolertinib shows promise in untreated EGFR-variant metastatic NSCLC

Blood-based biomarkers may aid earlier diagnosis of Alzheimer’s disease

Blood-based biomarkers (BBBs) may potentially aid earlier detection of Alzheimer’s disease (AD) following a recent revision of diagnostic criteria supporting core biomarker–based diagnosis. Initial local experience with lecanemab, a disease-modifying therapy (DMT) for patients with mild cognitive impairment or mild dementia due to AD, was shared at Advances in Medicine (AIM) 2025.

Blood-based biomarkers may aid earlier diagnosis of Alzheimer’s disease

01 Jul 2025

Adjuvant pertuzumab delivers survival gain in HER2+ EBC

The APHINITY trial of adding pertuzumab to adjuvant therapy for early HER2+ breast cancer turns in a significant OS improvement, with results presented at ESMO Breast Cancer 2025 concluding a phase III trial spanning over a decade

Adjuvant pertuzumab delivers survival gain in HER2+ EBC

Tofacitinib better than azathioprine as maintenance in steroid-responsive acute severe UC

In patients with steroid-responsive acute severe ulcerative colitis (UC), maintenance therapy with tofacitinib appears to be more effective at maintaining remission when compared with azathioprine, according to a study.

Tofacitinib better than azathioprine as maintenance in steroid-responsive acute severe UC

Plant-based diet improves postprandial glycaemia in T1D

Consumption of whole plant-based foods results in improvements in health outcomes among individuals with type 1 diabetes (T1D), suggests a study.

Plant-based diet improves postprandial glycaemia in T1D