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Patients with advanced solid tumours who have been treated according to matched targetable genomic mutation exhibit significantly longer overall survival than those who received standard-of-care (SOC) treatment, according to a Philippines study presented at ESMO Asia 2023.

Liquid NGS helps prolong survival in patients with advanced solid tumours

Faecal microbiota spores deliver benefit in older patients with C. diff recurrence

In an integrated analysis of two phase III ECOSPOR trials presented at AIBD 2023, faecal microbiota spores (ie, live-brpk) demonstrated favourable safety and efficacy signals for the treatment of recurrent Clostridioides (C.) difficile infection (CDI) in older individuals.

Faecal microbiota spores deliver benefit in older patients with C. diff recurrence

22 Dec 2023

10-year study: High incidence and mortality of acquired haemophilia A in HK

A retrospective, territory-wide, 10-year study has shown high incidence and mortality of acquired haemophilia A (AHA) in Hong Kong. Immunosuppression-related sepsis was the major cause of mortality, indicating the need for individualized immunosuppressive therapy (IST).

10-year study: High incidence and mortality of acquired haemophilia A in HK

Nocturnal reflux, snoring linked to increased risk of asthma, respiratory problems

People with nocturnal gastroesophageal reflux (GER) and habitual snoring are vulnerable to developing asthma and respiratory symptoms, according to a study.

Nocturnal reflux, snoring linked to increased risk of asthma, respiratory problems

Risankizumab as induction therapy induces clinical remission in UC

Induction therapy with risankizumab, a monoclonal antibody neutralizing interleukin-23p19, resulted in significantly higher clinical remission rates among patients with moderate-to-severe ulcerative colitis (UC) compared with placebo, according to the INSPIRE trial presented at AIBD 2023.

Risankizumab as induction therapy induces clinical remission in UC

Acitretin plus triamcinolone treats oral lichen planus better than triamcinolone monotherapy

The combination of oral acitretin plus topical triamcinolone acetonide (TAC) appears to have superior efficacy than TAC alone in the treatment of patients with oral lichen planus, as shown in a study.

Acitretin plus triamcinolone treats oral lichen planus better than triamcinolone monotherapy

Abiraterone plus prednisolone, enzalutamide a toss-up in castration-resistant prostate cancer

21 Dec 2023 bởi

The combination of abiraterone plus prednisolone appears to have similar efficacy and safety as enzalutamide in the treatment of patients with nonmetastatic castration-resistant prostate cancer, according to a study.

Abiraterone plus prednisolone, enzalutamide a toss-up in castration-resistant prostate cancer

21 Dec 2023

Routine testing for enterovirus CNS infection a must in febrile infants: study

Infants with human nonpolio enterovirus (EV) central nervous system (CNS) infection often present without cerebrospinal fluid (CSF) pleocytosis, reports a study.

Routine testing for enterovirus CNS infection a must in febrile infants: study

Somapacitan safe, effective in children with growth hormone deficiency

21 Dec 2023 bởi

Use of somapacitan, a long-acting growth hormone (GH) derivative, for 2 years is efficacious and well tolerated in prepubertal children with GH deficiency (GHD), reports a study.

Somapacitan safe, effective in children with growth hormone deficiency

21 Dec 2023

Serum DHEA, testosterone levels inversely linked to CAC in older men

In older men, serum levels of dehydroepiandrosterone (DHEA) and testosterone correlate inversely with coronary artery calcification (CAC), partially independently from each other, a study has shown.

Serum DHEA, testosterone levels inversely linked to CAC in older men