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Tislelizumab a new Tx alternative for very high-risk bladder cancer?
In the phase II pilot TRUCE-02 trial, tislelizumab plus low-dose nab-paclitaxel shows promising clinical antitumour activity and is well tolerated in patients with extensive very high-risk (VHR) non-muscle-invasive bladder cancer (NMIBC) who are ineligible for or decline radical cystectomy (RC).
Tislelizumab a new Tx alternative for very high-risk bladder cancer?
06 Mar 2025
App-based intervention cuts depression rate in youths with insomnia by >40 percent
App-based cognitive behavioural therapy for insomnia (CBT-I) reduces the incidence of depression in youths with insomnia by >40 percent, researchers from the Chinese University of Hong Kong (CUHK) and Peking University Sixth Hospital have reported.
App-based intervention cuts depression rate in youths with insomnia by >40 percent
06 Mar 2025
Leisure-time physical activity helps prevent hepatic steatosis
Leisure-time physical activity (PA) offers protection against hepatic steatosis, with greater benefits seen among women and young people, suggests a study. Additionally, increasing leisure-time PA in men helps prevent liver fibrosis.
Leisure-time physical activity helps prevent hepatic steatosis
05 Mar 2025
EV-302 2-year updates: EV+P maintains transformative benefit in bladder cancer
The updated analysis of the phase III EV-302 trial continues to show the benefit of front-line enfortumab vedotin plus pembrolizumab (EV+P) compared with chemotherapy in patients with previously untreated locally advanced or metastatic urothelial carcinoma (la/mUC).