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Switching to DOACs may prevent stroke, bleeding in older adults

16 Aug 2025

Older patients on a vitamin K antagonist (VKA) derive benefits from switching to standard-dose (SD) direct-acting oral anticoagulant (DOAC) as shown by significant decreases in stroke or systemic embolism, fatal and intracranial bleeding, and death, reveals a study.

Switching to DOACs may prevent stroke, bleeding in older adults

16 Aug 2025

Prenatal SSRI, SNRI exposure linked to elevated risk of PPH

16 Aug 2025

Women with prenatal exposure to selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs and SNRIs) are at increased risk of postpartum haemorrhage (PPH), although residual confounding cannot be ruled out, as reported in a study.

Prenatal SSRI, SNRI exposure linked to elevated risk of PPH

16 Aug 2025

Advancing collaboration in COVID-19 care

16 Aug 2025

Held in June 2025 in Singapore, the Pfizer COVID-CONNECT Masterclass convened international experts to discuss the evolving challenges of COVID-19. Co-chaired by Dr Asok Kurup and Dr Luke Moore, this event assessed the ongoing global impact of the disease and explored evidence-based strategies across the patient journey from early identification to effective treatment.

Advancing collaboration in COVID-19 care

16 Aug 2025

Oseltamivir for influenza helps reduce neuropsychiatric events

15 Aug 2025

The use of oseltamivir for treating influenza episodes in children appears to lower the risk of serious neuropsychiatric events, according to a retrospective cohort study.

Oseltamivir for influenza helps reduce neuropsychiatric events

15 Aug 2025

No mortality benefit with longer antibiotic prophylaxis durations in cirrhosis, upper GI bleeds

15 Aug 2025

In patients with cirrhosis and upper gastrointestinal (GI) bleeds, mortality outcome does not differ between shorter and longer antibiotic prophylaxis durations, according to a systematic review and Bayesian meta-analysis.

No mortality benefit with longer antibiotic prophylaxis durations in cirrhosis, upper GI bleeds

15 Aug 2025

COVID-19 and beyond: Viral infections, preparedness, and long-term impact

15 Aug 2025

At the recent COVID-CONNECT Masterclass, an expert-led session explored where COVID-19 stands among common viral infections today. In a non-promotional symposium supported by Pfizer, infectious disease specialist Dr Leong Hoe Nam, Mount Elizabeth Hospital Novena, Singapore, discussed strategies for managing viral infections and surge preparedness. Complementing this, Professor David Strain from the University of Exeter Medical School, UK highlighted the enduring burden of long COVID.

COVID-19 and beyond: Viral infections, preparedness, and long-term impact

15 Aug 2025

Radiotherapy plus sacituzumab govitecan feasible in metastatic breast cancer

14 Aug 2025

Concurrent administration of sacituzumab govitecan and radiotherapy is well tolerated and does not lead to increased toxicity in patients with metastatic breast cancer, a study has shown.

Radiotherapy plus sacituzumab govitecan feasible in metastatic breast cancer

14 Aug 2025

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

14 Aug 2025 bởi

The E-STOP trial presented at ESHRE 2025 supports early antibiotic suspension in paediatric patients with cancer and febrile neutropenia (FN).

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

14 Aug 2025

Peg-filgrastim reduces neutropenia in children with solid tumours

13 Aug 2025

The incidence of febrile neutropenia (FN) is significantly lesser in children with solid tumours receiving pegylated filgrastim as primary prophylaxis following chemotherapy than in those assigned to filgrastim alone, reports a study. Moreover, no adverse events attributed to the study drug have been observed.

Peg-filgrastim reduces neutropenia in children with solid tumours

13 Aug 2025

Ultrashort inpatient TB prevention feasible in advanced HIV, cryptococcal meningitis patients

13 Aug 2025 bởi

The IMPROVE trial shows the feasibility and safety of 1-month isoniazid and rifapentine (1HP) in an inpatient setting as tuberculosis preventive therapy (TPT) in patients with advanced HIV disease (AHD) and cryptococcal meningitis (CM).

Ultrashort inpatient TB prevention feasible in advanced HIV, cryptococcal meningitis patients

13 Aug 2025

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Switching to DOACs may prevent stroke, bleeding in older adults

Switching to DOACs may prevent stroke, bleeding in older adults

Prenatal SSRI, SNRI exposure linked to elevated risk of PPH

Prenatal SSRI, SNRI exposure linked to elevated risk of PPH

Advancing collaboration in COVID-19 care

Advancing collaboration in COVID-19 care

Oseltamivir for influenza helps reduce neuropsychiatric events

Oseltamivir for influenza helps reduce neuropsychiatric events

No mortality benefit with longer antibiotic prophylaxis durations in cirrhosis, upper GI bleeds

No mortality benefit with longer antibiotic prophylaxis durations in cirrhosis, upper GI bleeds

COVID-19 and beyond: Viral infections, preparedness, and long-term impact

COVID-19 and beyond: Viral infections, preparedness, and long-term impact

Radiotherapy plus sacituzumab govitecan feasible in metastatic breast cancer

Radiotherapy plus sacituzumab govitecan feasible in metastatic breast cancer

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

Study supports early antibiotic suspension in kids with cancer, febrile neutropenia

Peg-filgrastim reduces neutropenia in children with solid tumours

Peg-filgrastim reduces neutropenia in children with solid tumours

Ultrashort inpatient TB prevention feasible in advanced HIV, cryptococcal meningitis patients

Ultrashort inpatient TB prevention feasible in advanced HIV, cryptococcal meningitis patients