Tin tức & Cập nhật

In patients with type 1 diabetes (T1D) treated with SGLT2 inhibitors, such as dapagliflozin, the addition of pioglitazone helps to intensify the reduction in HbA1c and blocks the increase in plasma ketone driven by SGLT2 inhibitors, reports a study presented at ADA 2024. This enables long-term cardiovascular and renal outcome studies to be safely performed in T1D patients.

Use of antibiotics appears to increase the risk of Kawasaki disease (KD) in children, reveals a study. KD development is potentially driven by gut microbiota changes due to antibiotic use.

Findings from the phase III KRYSTAL-12 trial underpin the treatment potential of adagrasib for previously treated metastatic non-small cell lung cancer (NSCLC) harbouring a KRAS^G12C mutation.

In Singapore, short-acting β2-agonist (SABA) is often overused for asthma, especially in the specialist care setting, according to data from the SABINA III study.

Treatment with tildrakizumab in patients with moderate-to-severe scalp psoriasis helps reduce scalp itch and improve quality of life when compared with placebo, with no new safety signals, as shown in a phase IIIb study.

In patients with type 2 diabetes (T2D), moderate-intensity statin in combination with ezetimibe results in greater reductions in low-density lipoprotein cholesterol (LDL-C) and better prevention of adverse outcomes when compared with high-intensity statin monotherapy, suggests a study.