Bronchiolitis Disease Summary

Last updated: 05 May 2025

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Overview

Bronchiolitis is a disease of the lower respiratory tract characterized by acute inflammation and edema of the bronchioles, accompanied by an increase in mucus production as defined in the Introduction section.

Bronchiolitis usually affects children <2 years of age and is among the leading causes of hospitalization of infants in the United States and Asia.  A more detailed discussion on the prevalence of bronchiolitis can be found in the Epidemiology section.

The clinical features of bronchiolitis are largely because of airway obstruction and decreased lung compliance and further information regarding these are discussed in the Pathophysiology section.

The Etiology section discusses that most cases of bronchiolitis are caused by respiratory syncytial virus (RSV). Other etiologies are enumerated in this section.

History and Physical Examination

The Clinical Presentation section discusses the signs and symptoms of bronchiolitis and its course.

The Physical Examination section mentions the findings in patients with bronchiolitis during examinations.

Diagnosis

Bronchiolitis is diagnosed based on the patient’s history and presentation.  The Diagnosis or Diagnostic Criteria section enumerates the criteria for diagnosing bronchiolitis.

Tests and imaging that can be done for diagnosing bronchiolitis are discussed in the Laboratory Tests and Ancillaries and Imaging sections.

The Differential Diagnosis section enumerates the alternative diagnoses for bronchiolitis.

Management

Indications for hospitalization of patients with bronchiolitis are enumerated in the Evaluation section.

The Pharmacological Therapy section states that the therapy depends on the underlying etiology of bronchiolitis. This section discusses inhaled bronchodilators, nebulized saline solution, Ribavirin, xanthines and other medications that can be used in the management of patients with bronchiolitis.

The Nonpharmacological section discusses parental education, hydration and nutrition therapy, supplemental oxygen and non-invasive ventilation that can be part of management of patients with bronchiolitis.

Measures that can be taken to prevent the development of bronchiolitis are in the Prevention section.

Patient monitoring is an important part of the management of bronchiolitis. Measures to be taken in monitoring and discharge criteria are discussed in the Monitoring section.