Hemorrhoids Disease Summary

Last updated: 04 November 2025

Overview

Hemorrhoids are naturally occurring vascular structures located within the submucosa of the anal canal, consisting of loose connective tissue, smooth muscle (Treitz’s muscle), and blood vessels with numerous arteriovenous connections accounting for the bright red color of hemorrhoidal bleeding, as stated in the Introduction section.

Hemorrhoids affect approximately 4.4% of the global population, with the highest prevalence observed among individuals aged 45-65 years. A detailed discussion about the prevalence of hemorrhoids is in the Epidemiology section.

The Pathophysiology section states that hemorrhoids are associated with conditions that increase intra-abdominal pressure, leading to impaired venous return from the hemorrhoidal veins and a subsequent pathologic enlargement of the vascular cushions that results in symptomatic hemorrhoids. The development process of hemorrhoids is discussed in this section.

The Risk Factors section lists conditions that increase the likelihood of developing hemorrhoids.

The differences between external and internal hemorrhoids are explained in the Classification section.



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History and Physical Examination

The Clinical Presentation section describes the clinical features commonly seen in patients with hemorrhoids.

The History section contains important information that should be gathered during the evaluation of patients with hemorrhoids.

The Physical Examination section outlines the appropriate evaluation of patients with hemorrhoids and explains the use of anoscopy.

The Screening section lists the grading of internal hemorrhoids.

Diagnosis

Discussion in visualization procedures that will aid in the diagnosis of hemorrhoids is in the Imaging section. 

Other anorectal conditions that should be considered when evaluating symptoms suggestive of hemorrhoids are listed in the Differential Diagnosis section.

Management

Clinical decisions regarding treatment options in patients with hemorrhoids are explained in the Evaluation section.

General therapy principles of ablative office procedures and surgical hemorrhoidectomy in the management of hemorrhoids are in the Principles of Therapy section.

The Pharmacological Therapy section discusses in detail available pharmacologic preparations for the relief of hemorrhoidal symptoms such as analgesics, topical corticosteroids, herbal medicines and other agents.

The Nonpharmacological section includes things to educate the patient about the management of hemorrhoids and the importance of dietary modifications and other supportive measures. Different options for ablative office procedures are also discussed in this section. 

Options for surgical therapy such as open, closed and stapled hemorrhoidectomy are discussed in the Surgery section.