Ischemic Stroke Initial Assessment

Last updated: 26 September 2025

Content on this page:

Content on this page:

Clinical Presentation

An early and accurate diagnosis is essential in acute stroke management to confirm the presence of stroke, identify stroke mimics or other conditions requiring urgent care and determine the etiology for targeted interventions.



Ischemic Stroke_Initial AssesmentIschemic Stroke_Initial Assesment




Common Presentation of Patients with Acute Ischemic Stroke by Region  

Left (Dominant) Hemisphere  

The common presentations of a patient with an acute stroke in the left hemisphere include left gaze preference, right visual field deficit, right hemiparesis, right hemisensory loss, dysarthria, aphasia (Broca’s, Wernicke’s, Global), apraxia and visual agnosia.  

Right (Non-dominant) Hemisphere  

The common presentations of a patient with an acute stroke in the right hemisphere are right gaze preference, left visual field deficit, left hemiparesis, left hemisensory loss (hemispatial inattention), neglect of left side and dysarthria.  

Brainstem  

The common presentations of a patient with an acute stroke in the brainstem are nausea/vomiting, diplopia, dysconjugate gaze, gaze palsy, nystagmus, dysarthria, dysphagia, vertigo, syncope, hemiparesis or quadriplegia, sensory loss in the hemibody or on all four limbs, decreased consciousness, hiccups, abnormal respirations, and alexia or inability to understand words written.  

Cerebellum  

The common presentations of patients with an acute stroke in the cerebellum are truncal/gait ataxia, limb ataxia, dysarthria, vertigo and nystagmus.

History

The time of symptom onset is the single most important piece of historical information in the diagnosis of stroke. Stroke onset is defined as the last time the patient was symptom-free. Determine the symptom evolution and associated features that may point to alternative diagnoses (eg seizure, migraine, infection, trauma). Identify the risk factors for arteriosclerosis and cardiovascular (CV) disease; medications and conditions that may predispose to bleeding complications; and history of drug abuse, infection, migraine, seizure, trauma, oral contraceptive use, or pregnancy.

Physical Examination

A complete physical examination, including vital signs, oxygen saturation and body temperature, should be done. A focused neurologic exam is critical to rapidly assess deficits.

Diagnosis or Diagnostic Criteria

Clinical Stroke Score  

The National Institutes of Health Stroke Scale (NIHSS) helps quantify the degree or severity of neurological deficit and may identify the possible location of the lesion/occlusion. This facilitates communication between healthcare professionals and may provide prognostic information. This may identify patients eligible for interventions and potential risk for complications. The Rapid Arterial Occlusion Evaluation Scale (RACE) or the Los Angeles Motor Scale (LAMS) may be used to identify suspected stroke patients with increased likelihood of large vessel occlusion who are candidates for endovascular thrombectomy.