Paget's Bone Disease Disease Summary

Paget's bone disease, also known as osteitis deformans, is characterized by a significant increase in bone resorption and turnover in localized parts of the skeleton causing enlargement and thickening of the bone that is disordered and architecturally unstable.
Bone or joint pain is the most common symptom, although patients may be asymptomatic for a long period of time before signs and symptoms occur.
Diagnosis of Paget's bone disease includes performing laboratory tests like serum alkaline phosphatase (ALP) and serum calcium, and imaging.
Goals of treatment are to ease pagetic pain, reduce activity of the disease, obtain full remission and prevent complications.

For further information regarding the management of Paget's Bone Disease, please refer to Disease Algorithm for the Treatment Guideline.