Pediatric Academic Societies (PAS) 2023 Meeting
Washington DC, US 27 April 2023 - 01 May 2023
Higher vitamin D dose beneficial for paediatric obesity-related asthma
A 50,000-IU loading dose of oral vitamin D plus 8,000 IU daily is effective and safe for increasing serum 25(OH)D levels to ≥40 ng/mL in children and adolescents with asthma who were overweight or obese, as opposed to the standard of care (SoC) dose of 600 IU daily, according to findings from the VDORA1* trial.
Dupilumab cuts exacerbations, improves lung function in paediatric asthma patients with high eosinophils
In the post hoc analysis of data from the phase III LIBERTY ASTHMA VOYAGE study, the monoclonal antibody dupilumab reduced exacerbations and improved lung function in children aged between 6 and 11 years with moderate-to-severe asthma and baseline blood eosinophil count of ≥500 cells/μL.
In-utero exposure to poor air quality a risk factor for childhood ADHD
Children born to mothers who were exposed to polluted air while pregnant are at increased risk of childhood attention-deficit hyperactivity disorder (ADHD), according to a study presented at PAS 2023.
