Ruxolitinib: The first and only US FDA–approved topical repigmentation treatment for vitiligo
11 Sep 2025
byDr. Chau-Yee Ng, Vitiligo Clinic and Pigment Research Center, Chang Gung Memorial Hospital, Taipei, Taiwan
Vitiligo, a chronic autoimmune condition characterized by
skin depigmentation, significantly impacts patients’ quality of life (QoL) and
psychosocial well-being. At a symposium held during the Advances in Medicine
(AIM) 2025 conference, Dr Chau-Yee Ng of the Vitiligo Clinic and Pigment
Research Center, Chang Gung Memorial Hospital, Taipei, Taiwan, shared latest
advances in vitiligo research, highlighting US FDA’s approval of ruxolitinib
cream (Lumirix®, Rxilient Medical), the first topical Janus kinase
(JAK) inhibitor designed to target repigmentation in vitiligo.