News &amp; Updates

A short-course antibiotic treatment for children with community-acquired pneumonia (CAP) demonstrates effectiveness similar to the long-course regimen but with fewer serious adverse events (AEs), reports a study.

Short-course antibiotic for paediatric CAP on par with long-course regimen

Ceftazidime-avibactam, ceftolozane-tazobactam safe for use in children

Treatment with either ceftazidime-avibactam (CAZ/AVI) or ceftolozane-tazobactam (C/T) is well tolerated and effective in children infected with Gram-negative pathogens resistant to carbapenems, a recent study has shown.

Ceftazidime-avibactam, ceftolozane-tazobactam safe for use in children

Flu shot during pregnancy extends protection to offspring

02 Jul 2025

Influenza vaccination in pregnant women, especially during the second or third trimester, cuts the risk of infection in infants, as shown in a study.

Flu shot during pregnancy extends protection to offspring

02 Jul 2025

Symptoms for ARIs in children vary across age groups

Acute respiratory infections (ARIs) are associated with various symptoms across different age groups, according to a Korea study.

Symptoms for ARIs in children vary across age groups

Capsular switching and emergence of vaccine escape variants after PCV introduction

While pneumococcal conjugate vaccines (PCVs) have greatly reduced the global burden of pneumococcal disease, the emergence of disease caused by non-vaccine type (NVT) pneumococci, through serotype replacement and/or serotype (capsular) switching, remains a significant challenge. This article reviews the process of vaccine escape by capsular switching and the resulting impact on PCVs’ effectiveness.

Capsular switching and emergence of vaccine escape variants after PCV introduction

Inclisiran confers LDL–C-lowering benefit in adolescents with HoFH

29 Jun 2025

In adolescents with homozygous familial hypercholesterolemia (HoFH), treatment with inclisiran appears to be safe and efficacious for reducing low-density lipoprotein cholesterol (LDL-C) levels, according to the results of the first part of the phase III ORION-13* trial.

Inclisiran confers LDL–C-lowering benefit in adolescents with HoFH

29 Jun 2025

Infant psychomotor development not harmed by biologic exposure in utero, during breastfeeding

Exposure to biologics for inflammatory bowel disease (IBD) in utero or during breastfeeding does not appear to impair psychomotor development in infants, according to a study.

Infant psychomotor development not harmed by biologic exposure in utero, during breastfeeding

Narcolepsy tied to increased risk of subclinical CVD

Individuals with narcolepsy, including children, appear to have an elevated risk of subclinical cardiovascular disease (CVD), according to a retrospective study.

Narcolepsy tied to increased risk of subclinical CVD