Varicella Differential Diagnosis

Last updated: 15 December 2025

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Differential Diagnosis

Varicella  

Other skin eruptions that may be confused with varicella zoster virus infection include:

  • Viral exanthems
  • Impetigo
  • Insect bites
  • Scabies
  • Erythema multiforme 
  • Papular urticaria
  • Drug eruption
  • Hand-foot-mouth disease
  • Disseminated herpes zoster
  • Other vesicular dermatoses with the same diffused rash typical of varicella

Herpes Zoster  

Pain experienced with herpes zoster is often misdiagnosed as the following:

  • Myocardial infarction
  • Pleurisy
  • Cholecystitis
  • Appendicitis
  • Duodenal ulcer
  • Ovarian cyst
  • Herniated intervertebral disc
  • Thrombophlebitis
  • Renal or biliary colic
  • Zoster sine herpete (dermatomal pain with positive serologic and virologic evidence but without rash)

Zoster rash may be confused with the following:

  • Impetigo
  • Contact dermatitis
  • Folliculitis
  • Scabies
  • Insect bites
  • Urticaria
  • Candidal infection
  • Dermatitis herpetiformis
  • Eczema herpeticum
  • Drug eruptions