G-EYE improves polyp, adenoma, and serrated polyp detection in colonoscopy

The G-EYE tool helps enhance the polyp (PDR), adenoma (ADR), and serrated polyp detection rates (SPDR) during colonoscopy, suggest the results of a meta-analysis.

A total of 143 articles were identified, of which three with 3,838 total colonoscopies were included in the meta-analysis. The pooled ADR (odds ratio [OR], 1.744, 95 percent confidence interval [CI], 1.534‒1.984; p<0.001), PDR (OR, 1.766, 95 percent CI, 1.547‒2.015; p<0.001), and SPDR (OR, 1.603, 95 percent CI, 1.176‒2.185; p=0.003) demonstrated significant improvements with G-EYE.

In addition, the G-EYE group showed a higher withdrawal time (mean difference, 0.114, 95 percent CI, 0.041‒0.186; p=0.002).

“Further studies are needed to evaluate the effect of G-EYE on interval colorectal cancer (CRC) and mortality rate,” the investigators said.

In this study, a team of investigators performed a literature search through 21 March 2023 using the databases of Embase, Medline, Cochrane Central Register of Controlled Trials, Web of Science Core Collection, KCI‒Korean Journal Index, and Global Index Medicus. They looked for core concepts of G-EYE, colonoscopy, ADR, PDR, SPDR, and withdrawal time.

A statistical analysis was also conducted using OpenMeta[Analyst]. Finally, the DerSimonian-Laird method and random effects model were utilized to pool data.

“Colonoscopy is the gold-standard test to decrease mortality from CRC,” the investigators said. “G-EYE is an inflated balloon on the bending section of the scope with the ability to flatten the folds to improve the ADR.”