Infertility Differential Diagnosis

Differential Diagnosis

Impaired Fertility Caused by Other Endocrine Dysfunctions  

Menstrual disorders can also be manifestations of underlying endocrine dysfunction. Screening is not routine but required if suggested in the history and physical exam. Hypersecretion of growth hormone (GH) in acromegaly can lead to loss of fertility. Diabetes mellitus can reduce gonadotropin-releasing hormone and luteinizing hormone response, which may lead to amenorrhea and oligomenorrhea. Obesity and metabolic syndrome can cause insulin resistance and hyperinsulinemia, which disrupt ovulation.