News &amp; Updates

Neoadjuvant nivolumab plus ipilimumab followed by chemoradiation and maintenance nivolumab yields high survival rates in locally advanced cervical cancer (LACC), according to final survival data from the phase II COLIBRI-1 trial.

Dual immune checkpoint blockade delivers encouraging survival benefit in LACC

Switching to entecavir reduces relapse, flare in HBeAg-negative patients

In hepatitis B e antigen-negative (HBeAg) patients, the last antiviral agent used prior to end of therapy (EOT) appears predictive of the timing of clinical relapse, according to a study. An entecavir-switching strategy may prevent relapse and reduce hepatitis flare and its severity within 24 weeks after EOT.

Switching to entecavir reduces relapse, flare in HBeAg-negative patients

Pulse steroid therapy tied to bone turnover marker suppression, but not BMD loss

Pulse intravenous methylprednisolone does not induce short-term loss of lumbar spine or hip bone mineral density (BMD), reports a Singapore study. However, it does suppress bone turnover markers, suggesting early effects on bone remodelling that are not captured by BMD alone.

Pulse steroid therapy tied to bone turnover marker suppression, but not BMD loss

Anticoagulants up risk of bleeding after esophageal dilation procedure

Patients taking anticoagulant medications at the time of esophageal dilation are at increased risk of experiencing gastrointestinal bleeding after the procedure, suggests a study.

Anticoagulants up risk of bleeding after esophageal dilation procedure

Pooled analysis validates iptacopan safety for PNH

A pooled analysis presented at EHA 2026 demonstrates the long-term safety of the oral proximal complement inhibitor iptacopan in the treatment of paroxysmal nocturnal haemoglobinuria (PNH).

Pooled analysis validates iptacopan safety for PNH

6-session exercise programme brings sustained benefits to knee OA patients awaiting TKR

A structured, physiotherapist-led six-session exercise programme provides sustained symptomatic and functional improvements to patients with end-stage knee osteoarthritis (OA) awaiting total knee replacement (TKR), a large real-world study in Hong Kong has shown.

6-session exercise programme brings sustained benefits to knee OA patients awaiting TKR

06 Jul 2026

High-dose cannabidiol offers relief in patients with chronic neuropathic pain

In the treatment of patients with chronic neuropathic pain, high-dose cannabidiol (CBD) helps reduce pain intensity and is well-tolerated, according to a crossover study.

High-dose cannabidiol offers relief in patients with chronic neuropathic pain

Upfront immunosuppression regimen improves survival in acquired haemophilia A

05 Jul 2026 by

In the first-line treatment of acquired haemophilia A (AHA), the use of an intravenous (IV) pulse-dose immunosuppression regimen that combines cyclophosphamide, dexamethasone, and rituximab appears to result in faster remission and improved survival compared with traditional oral sequential prednisone-based regimens, according to a study.

Upfront immunosuppression regimen improves survival in acquired haemophilia A

CGM plus virtual program improves HbA1c, weight in T2D adults with overweight/obesity

Continuous glucose monitoring (CGM) combined with a digital weight management program results in significant improvements in HbA1c, body weight, and other glucose metrics relative to usual care among adults with type 2 diabetes (T2D) and overweight or obesity, according to a study.

CGM plus virtual program improves HbA1c, weight in T2D adults with overweight/obesity

COPD exacerbations up risk of cardiopulmonary complications

In patients with chronic obstructive pulmonary disease (COPD), acute exacerbations contribute to an increased risk of cardiopulmonary complications, as shown in a retrospective cohort study.

COPD exacerbations up risk of cardiopulmonary complications