ADHD, depression up risk of orgasmic disorder in women

Women with attention-deficit/hyperactivity disorder (ADHD), with severe depression, and who engage in penetrative sex are at increased risk of female orgasmic disorder (FOD), suggests a study.

This case-control study included 221 Dominican women, of whom 107 had been diagnosed with FOD (case group) and 114 had no sexual dysfunction (control group). ADHD diagnosis was obtained from medical records, previously conducted using the DSM-5-TR criteria. The authors then assessed the severity of depressive symptoms in the two groups using the Beck Depression Inventory II.

FOD showed a significant association with ADHD and depression. Multivariate analysis revealed the highest risk of FOD among women with ADHD (odds ratio [OR], 4.91, 95 percent confidence interval [CI], 2.46‒9.20; p<0.001), those with severe depression (OR, 2.50, 95 percent CI, 1.08‒6.96; p=0.04), and those who had penetrative sexual intercourse (OR, 2.02, 95 percent CI, 1.03‒3.98; p=0.04).

“These findings may have important implications for the prevention and treatment of sexual disorders in women,” the authors said.

The study selected all diagnosed cases of FOD but not a specific subgroup. It was also conducted in a single clinic only, and its design did not allow for statements about causality to be made.

“FOD is listed in the DSM-5 and is defined as the persistent or recurrent inability to have an orgasm,” the authors said. “Many depressed women may experience sexual dysfunction, including FOD.”