Precision in action: Targeted strategies across the cancer care continuum

18 Oct 2026
Mary Joyce G. Tan, MD
Mary Joyce G. Tan, MDMedical Doctor; Medical Writer; MIMS
Mary Joyce G. Tan, MD
Mary Joyce G. Tan, MD Medical Doctor; Medical Writer; MIMS
Precision in action: Targeted strategies across the cancer care continuum

Precision oncology is changing how clinicians approach cancer—from intervening earlier in high-risk disease to overcoming treatment resistance and targeting actionable molecular drivers.1-4 Eli Lilly oncology developments build on these principles.

Primarily, long-term monarchE findings show that precisely targeting high-risk early breast cancer (EBC) with abemaciclib (Yulareb) delivers benefit that outlasts the two-year treatment course itself.1 That same precision extends to different malignancies with pirtobrutinib’s (Jaypirca) local approval, providing an option in addressing treatment resistance in chronic lymphocytic leukemia (CLL) while focus on RET-directed approach gives light to an upcoming treatment modality.2-4  

To better understand how these molecules help patients across their cancer journey, access the infographic below.  
REFERENCES: 1. Johnston S, et al. Ann Oncol 2026;37:155-165. 2. Sharman JP, et al. J Clin Oncol 2025;43:2538-2549. 3. Zhou C, et al. N Engl J Med 2023;389:1839-1850. 4. Hadoux J, et al. N Engl J Med 2023;389:1851-1861 5. Davie A, Traoré S, Badreldin W, et al. Adv Ther 2025;42(6):2767-2781 6. Chang SH, Svensson M, Hsin-Min Wang G, et al. J Manag Care Spec Pharm 2024;30:942-953. 7. Sledge GW Jr, Toi M, Neven P, et al. JAMA Oncol 2020;6(1):116-124. 8. Goetz MP, et al. Ann Oncol 2024;35:718-727. 9. Pal Singh S, et al. Mol Cancer 2018;17:57. 10. Hendriks RW, et al. Nat Rev Cancer 2014;14:219-232. 11. Tasso B, et al. Molecules 2021;26:7411 12. Gu D, et al. J Hematol Oncol 2021;14:40. 13. Wu JJ, et al. Leuk Lymphoma 2024;65:1609-1622. 14. Kangal-Shamanna R, et al. Cancer 2019;125:559-574. 15. Regua AT, Najjar M, Lo HW. Front Oncol 2022;12:932353.16. Belli C, et al. Ann Oncol 2021;32:337-350.

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Precision in Action: Targeted strategies across the cancer care continuum Precision in Action: Targeted strategies across the cancer care continuum

Precision in Action: Targeted strategies across the cancer care continuum