Cando
et al. (2024) provided a comprehensive overview of the burden, diagnosis,
management, and challenges of diabetes mellitus in the Philippines. Diabetes
mellitus, particularly type 2 diabetes (T2D), poses a growing threat to the
country’s healthcare system. The disease affects approximately 4.3 million
Filipinos, with an additional 2.8 million reportedly undiagnosed as of 2021.
This number is expected to increase, reaching 7.5 million by 2045, signaling a
significant public health concern. [
DMS: CRR 2024;(18)2:102951]*
The
country’s National Nutrition survey, the authors said, showed that impaired
fasting glucose rose from 7.4 percent in 2013 to 27.7 percent in 2019, which
reportedly reflects the poor metabolic health of Filipinos. They noted that a local
cohort study confirmed growing rates of diabetes and prediabetes. [
Diabetes Res Clin Pract 2009;86(2):130-133]
This worsening trend is fueled by both clinical and molecular risk factors,
such as obesity, sedentary lifestyles, dyslipidemia, and genetic
predispositions.
Obesity, diet, physical activity
Clinically,
obesity and poor diet are strongly linked to rising diabetes rates. Cando et
al. noted that 36.6 percent of adults in
the Philippines were overweight or obese as of 2019. Urban residents are reportedly
especially vulnerable, likely due to the availability of processed foods and
reduced physical activity. Furthermore, they also noted that the mean
Alternative Healthy Eating Index score for Filipinos was under 20/100,
substantially lower than that of neighboring countries. This poor diet quality
is said to reflect the socio-economic challenges many Filipinos face, such as
food insecurity and high poverty rates.
Physical
inactivity is another significant risk factor. Over 40 percent of Filipino
adults, the authors said, are physically
inactive, a figure exacerbated during the COVID-19 pandemic. Additionally,
dyslipidemia is highly prevalent, with 47 percent having high total cholesterol
and over seventy percent exhibiting low HDL levels. Gestational diabetes
mellitus (GDM) and polycystic ovarian syndrome (PCOS) also increase the risk of
developing T2D, particularly among women.
Genes
From
a molecular perspective, Cando et al. said that several genetic and epigenetic
factors have been identified as contributors to diabetes susceptibility in the
Filipino population. Studies reportedly found that specific gene variants such
as CDKAL1 and SERPINF1 are strongly linked with the disease. Moreover,
epigenetic research suggests that environmental and lifestyle factors can
modify gene expression, which may partially explain why Filipino immigrants to
the U.S. show higher diabetes rates.
Effects on the organs
Diabetes
significantly impacts various organ systems. Microvascular issues like
retinopathy and nephropathy are said to be prevalent. Diabetic retinopathy, in particular,
is reportedly the leading cause of preventable blindness in some Philippine
regions. The authors said that 42 percent of patients suffer from diabetic
neuropathy, while diabetic nephropathy contributes to 38 percent of renal
diseases nationally.
Macrovascular
complications such as heart disease and stroke are also prominent. Diabetes
increases the risk of coronary artery disease and cerebrovascular incidents. Cando
et al. noted that in the 2008 DiabCare survey, 10.5 percent of diabetic
patients reported angina, and 4.7 percent had experienced a stroke. According
to the article, these figures show that diabetes is not just a metabolic
disorder but a systemic one with far-reaching effects.
The
nonvascular complications are equally concerning. These, the authors said, are said to include gastrointestinal and
genitourinary issues, dermatologic conditions, and infectious diseases; likewise,
patients are said to be more susceptible to infections and slower wound
healing. Reportedly, 10.9 percent of diabetic patients in the same DiabCare
survey suffered from either skin, urinary tract, or respiratory infections.
Management
When
it comes to management, the Philippines is reported to largely follow the
American Diabetes Association’s standards. As Cando et al. noted, both local
and international guidelines recommend lifestyle modifications and metformin as
first-line treatments. For patients with more severe hyperglycemia,
pharmacological treatments are initiated earlier. However, the Philippine
Clinical Practice Guidelines (CPG) have not been updated since 2014 [editor’s
note: the updated CPG has now been made available in 2025]. This lag, they said,
in updating reflects the need for modernization, particularly in integrating
newer drug classes like SGLT-2 inhibitors and GLP-1 receptor agonists, which
are reportedly effective but costly.
Access
to medications is another challenge. While metformin and sulfonylureas are
widely accessible, Cando et al. reported that newer medications are not readily
available in public healthcare settings. The Philippine National Formulary
includes only a limited selection of anti-diabetic drugs. Although insulin is
available through the government's Insulin Access Program, usage remains low
due to cost, needle phobia, and lack of education.
Complementary
and alternative medicines like bitter melon (
Momordica charantia), locally known as
“ampalaya”, and the insulin plant (
Costus igneus) are popular among Filipinos.
According to the authors, while some studies suggest potential glucose-lowering
effects, most clinical trials remain inconclusive due to small sample sizes and
poor methodologies.
A
critical component of diabetes care is self-management. The authors noted that
Filipino patients show varied adherence to self-care behaviors such as diet,
exercise, and blood glucose monitoring. In one cross-sectional study they
reported in the outpatient department of a public tertiary hospital in the
country , only 50 percent followed healthy eating guidelines, while just 46
percent maintained physical activity. Blood glucose monitoring was the least followed,
with 75 percent checking levels only 1–3 times per week. Medication adherence
was reportedly high at over 76 percent, but barriers like low health awareness,
poor provider-patient communication, and limited access to services were
common. [
J ASEAN Fed
Endocr Soc 2013;28(2): 134]
Burden
The
economic burden of diabetes in the Philippines is reported to be substantial.
The average diabetes-related expenditure, as Cando et al. reviewed, rose from
USD61 in 2010 to USD450.8 in 2021. Healthcare, they said, is largely funded
through out-of-pocket payments, making diabetes management unaffordable for
many. PhilHealth, the national health insurance provider, offers some support,
but its Primary Care Benefit package is limited to indigent and sponsored members.
The PhilPEN program provides basic services at the barangay level but lacks
coverage for more advanced needs.
The
cost of complications exacerbates the financial burden. As Cando et al. reported,
a study revealed that patients with complications spent significantly more—up
to five times higher annually—than those without. These costs are mainly
attributed to dialysis, surgery, and non-diabetes-related drugs. [
BMJ Open 2021;11(10):
Article e049737]
Current initiatives and the future
In
terms of national initiatives, Cando et al. also said that the Department of
Health has implemented several programs, including the National Diabetes
Prevention and Control Plan and the Insulin Medicine Access Program (InMAP).
Localized projects like the First Line Diabetes Care (FiLDCare) and
community-based education programs have shown promise. Reportedly, these
initiatives led to improved HbA1c levels and increased awareness, but their
reach is said to remain limited due to geographic and infrastructural
challenges.
The
authors also touched on how the COVID-19 pandemic further strained the diabetes
care system. The government, they noted, issued policies allowing electronic
prescriptions and encouraged telemedicine, but these solutions were limited by
internet access and digital literacy, reflecting the fragility of diabetes care infrastructure,
particularly in times of crisis.
The
authors stressed that diabetes care in the Philippines must be transformed
through improved healthcare access, updated clinical guidelines, and expanded
health insurance coverage. They saw that the implementation of the Universal
Health Care (UHC) Act and support from international frameworks like the WHO’s
Global Diabetes Compact are pivotal, but they noted that real progress will
require not only policy shifts but also systemic improvements in healthcare
delivery, education, and research.
Cando et al. said that there is also a pressing need for more diabetes-focused
studies in the country to inform evidence-based policymaking. They encouraged public
and private sector collaboration, increased health budget allocations, and the
promotion of healthier lifestyles. Without these changes, the growing burden of
diabetes will continue to strain the healthcare system and diminish the quality
of life for millions of Filipinos.
*Cando LFT, Quebral EPB, Ong EP, Catral CDM,
Relador RJL, Velasco AJD, Alcazar RMU, Reyes NAL, Pilotin EJB, Ornos EDB. Current
status of diabetes mellitus care and management in the Philippines.DMS: CRR 2024;(18)2:102951.