Melasma Disease Summary

Last updated: 08 August 2025

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Content on this page:

Overview

Melasma is an acquired hyperpigmentary skin disorder characterized by irregular light to dark brown macules occurring in the sun-exposed areas of the face, neck and arms, as stated in the Introduction section.

The prevalence of melasma varies according to ethnicity, sunlight intensity, and skin phototype. A detailed discussion about the prevalence of melasma is in the Epidemiology section.

The Pathophysiology section states that melasma involves various factors that lead to enhanced melanin production.



Melasma_Disease SummaryMelasma_Disease Summary




The Classification section lists the different types of melasma and describes their appearance under the Wood’s lamp exam.  

History and Physical Examination

The Physical Examination section discusses classification of melasma based on its clinical pattern on examination.

The Screening section features the Melasma Area and Severity Index (MASI) or modified MASI (mMASI) in evaluating the severity of melasma. 

Diagnosis

The importance of the Wood’s lamp exam in classifying melasma is in the Laboratory Tests and Ancillaries section.

Other diseases that should be ruled out in the diagnosis of melasma are listed in the Differential Diagnosis section.

Management

The Pharmacological Therapy section discusses in detail treatment options for melasma such as chemical peels, topical corticosteroids, topical depigmenting agents, topical retinoids, systemic agents, and other therapies.

The Nonpharmacological section includes things to educate the patient about the management of melasma. Lifestyle modifications such as sunscreens and camouflage makeup are also discussed in this section.

The Surgery section explains different modalities in the management of melasma, such as cryosurgery, intense pulse light, laser therapy, light emitting diode, microneedling and pulsed dye laser.