Dry Eye Syndrome Tóm tắt về bệnh

Cập nhật: 22 May 2025

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Tổng quan

Dry eye syndrome is a common condition that leads to varying degrees of eye discomfort, with a global prevalence of 5-50%. It is also called dry eye disease, keratoconjunctivitis sicca or dysfunctional tear syndrome. The definition of dry eye syndrome and its prevalence can be found in the Introduction and Epidemiology sections.

The ocular symptoms of dry eye syndrome are secondary to several factors such as increased osmolarity of the tear film and inflammation of the ocular surface. Mechanisms that are involved in these factors are discussed in the Pathophysiology section. The Risk Factors section enumerates the different factors that predispose the patient to have dry eye syndrome.

The etiopathogenic and severity classifications of dry eye syndrome are identified and explained in the Classification section. 

History and Physical Examination

Initial signs and symptoms that a patient with dry eye syndrome may experience include blurry vision and burning sensation. Other symptoms are enumerated in the Clinical Presentation section.

Pertinent information that may predispose the patient to have dry eye syndrome is listed in the History section.

In the Physical Examination section, ophthalmological tests and neurological examinations to be done to the patient are discussed. 

Chẩn đoán

The Screening section enumerates the questionnaires that can be used in assessing patients with dry eye syndrome. Some examples of these questionnaires are the NEI-Visual Function Questionnaire (NEI-VFQ) and the Dry Eye Questionnaire (DEQ).

Diagnostic tests such as ocular surface dye staining and lacrimal gland function test that may be conducted to confirm the diagnosis of dry eye syndrome are enumerated in the Laboratory Tests and Ancillaries section.

Ophthalmological diseases present similar symptoms to dry eye syndrome that should be ruled out are in the Differential Diagnosis section.

Xử trí

Treatment of dry eye syndrome is directed towards alleviating patient symptoms. Treatment goals and different therapeutic strategies in the management of patients with dry eye syndrome are discussed in the Principles of Therapy section.

Details about artificial tears/lubricants and ophthalmological anti-inflammatory agents, secretagogues and antioxidants are in the Pharmacological therapy section. Biological tear substitutes are also in this section.

Patient education and tear retention devices are discussed in detail in the Nonpharmacological section.

Surgical options are reserved for severe dry eye syndrome. These are further discussed in the section of Surgery.

Follow up is needed to assess a patient’s response to therapy, and if further referral is needed. Things to be noted during patient follow-up are in the Monitoring section.