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Tổng quan
Endometrial cancer is a malignant tumor of the uterus that is
usually diagnosed in its early stages, as stated in the Introduction section.
Endometrial cancer is the sixth most common malignancy
worldwide and the 14th leading cause of cancer death in women
worldwide. A detailed discussion about
the prevalence of endometrial cancer is in the Epidemiology
section.
The Pathophysiology section states that endometrial
intraepithelial neoplasia (atypical endometrial hyperplasia) is the precursor
lesion to endometrial cancer according to the 1994 World Health Organization
(WHO) and International Endometrial Collaborative Group schemas.
The Risk Factors section enumerates the factors that
contribute to the development of endometrial cancer.
The different types of endometrial cancer and histology are
explained in the Classification
section.
Endometrial Cancer_Disease SummaryHistory and Physical Examination
The Clinical Presentation
section describes the clinical features suggestive of endometrial
cancer. A pelvic exam and full body examination are important in the evaluation
of endometrial cancer and are emphasized in the Physical Examination section.
The Screening section explains the recommendations for
screening in symptomatic women and those at increased risk for endometrial
cancer.
Chẩn đoán
Discussions on tumor markers, surgical diagnostic procedures
and other tests are in the Laboratory Tests and
Ancillaries section.
The Imaging section discusses different studies such as
magnetic resonance imaging (MRI), pelvic ultrasound, positron emission
tomography (PET) scan, chest radiography, and computed tomography (CT) scan
that are important in the evaluation of endometrial cancer.
Other conditions that should be ruled out in the diagnosis of
endometrial cancer are listed in the Differential
Diagnosis section.
Xử trí
The staging of endometrial cancer based on imaging studies,
histological results and surgery is discussed in the Evaluation section.
General therapy principles and management of endometrial
cancer based on the risk, disease stage and the patient’s desire for fertility are
explained in the Principles of Therapy
section.
The Pharmacological
Therapy section discusses in
detail the systemic therapy, biomarker-directed systemic therapy, and hormonal
therapy in the management of endometrial cancer.
The Nonpharmacological section explains the indications for
observation in patients with endometrial cancer whether they underwent surgery
or not.
Recommended surgical techniques based on the stage of
endometrial cancer are presented in the Surgery
section.
The Radiation Therapy
section discusses the treatment option for patients who are not qualified for
surgery.
The Monitoring
section identifies indications for follow-up in patients with endometrial
cancer based on the therapy done and treatment response.
The Prognosis section discusses the factors in
the evaluation of endometrial cancer.
The management of recurrent endometrial cancer is explained
in the Complications section.
