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Upadacitinib for non-segmental vitiligo hits targets in two phase III trials

27 Aug 2026 bởi

Once-daily oral treatment with the JAK inhibitor upadacitinib delivers clinically meaningful facial and total body repigmentation in adults and adolescents with non-segmental vitiligo, according to the phase III Viti-Up 1 and 2 trials.

Upadacitinib for non-segmental vitiligo hits targets in two phase III trials

27 Aug 2026

Drug interactions not uncommon in breast cancer patients on chemo

27 Aug 2026 bởi

Potential drug-drug interactions (DDIs) exist in breast cancer patients undergoing cyclin-dependent kinase (CDK) 4/6 inhibitors chemotherapy, suggests a study.

Drug interactions not uncommon in breast cancer patients on chemo

27 Aug 2026

Ribociclib improves survival in advanced breast cancer

26 Aug 2026

Ribociclib combined with letrozole or fulvestrant demonstrates robust progression-free (PFS) and overall survival (OS), with modest objective response rates in heavily pretreated patients with advanced breast cancer, according to a real-world study.

Ribociclib improves survival in advanced breast cancer

26 Aug 2026

Potential overuse seen in empiric antibiotic therapy for paediatric CSF infection

26 Aug 2026 bởi

Empiric antibiotic prescription patterns vary substantially in children with cerebrospinal fluid (CSF) shunt infection, and overuse is not uncommon, a study has found.

Potential overuse seen in empiric antibiotic therapy for paediatric CSF infection

26 Aug 2026

How do ARTs affect body composition in children living with HIV?

26 Aug 2026

In children living with HIV, treatment with dolutegravir and atazanavir/ritonavir (ATV/r) appear to yield greater gains in fat-free mass and muscle mass compared with lopinavir/ritonavir (LPV/r), a study has shown. By contrast, darunavir/ritonavir (DRV/r), tenofovir alafenamide (TAF), and prior exposure to nevirapine are associated with gains in fat mass.

How do ARTs affect body composition in children living with HIV?

26 Aug 2026

SG experts form CKD-aP guidelines for local practice

25 Aug 2026 bởi

Chronic kidney disease-associated pruritus (CKD-aP) is a debilitating condition that affects nearly half of patients undergoing dialysis, significantly impairing their quality of life (QoL), and requires multidisciplinary care, suggests a Singapore study.

SG experts form CKD-aP guidelines for local practice

25 Aug 2026

Immunosuppressant use among RA patients may protect against Alzheimer's disease

24 Aug 2026

Among patients with rheumatoid arthritis (RA), treatment with immunosuppressants may partly attenuate the risk of Alzheimer’s disease, according to a study.

Immunosuppressant use among RA patients may protect against Alzheimer's disease

24 Aug 2026

Higher-dose methimazole helps GD patients with severe thyrotoxicosis reach euthyroid status

23 Aug 2026

Methimazole given in a large dose allows individuals with severe thyrotoxicosis from Graves’ disease (GD) to achieve euthyroid status as fast as other GD patients, according to a study.

Higher-dose methimazole helps GD patients with severe thyrotoxicosis reach euthyroid status

23 Aug 2026

Puberty blockers ease mood disorders, suicidal thoughts in transgender youths

21 Aug 2026 bởi

Mood disorders and suicidal thoughts are more common among transgender youths compared with their cisgender peers, a study has found. Prescription of a puberty blocker may help lessen such disparity, indicating mental health benefits for transgenders.

Puberty blockers ease mood disorders, suicidal thoughts in transgender youths

21 Aug 2026

5-unit IV insulin prevents hypoglycaemia, reduces potassium in adults with hyperkalaemia

20 Aug 2026

Five-unit dosing of intravenous (IV) regular insulin results in lower hypoglycaemia incidence and comparable serum potassium decrease when compared with doses >5 units, according to a study.

5-unit IV insulin prevents hypoglycaemia, reduces potassium in adults with hyperkalaemia

20 Aug 2026

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Upadacitinib for non-segmental vitiligo hits targets in two phase III trials

Upadacitinib for non-segmental vitiligo hits targets in two phase III trials

Drug interactions not uncommon in breast cancer patients on chemo

Drug interactions not uncommon in breast cancer patients on chemo

Ribociclib improves survival in advanced breast cancer

Ribociclib improves survival in advanced breast cancer

Potential overuse seen in empiric antibiotic therapy for paediatric CSF infection

Potential overuse seen in empiric antibiotic therapy for paediatric CSF infection

How do ARTs affect body composition in children living with HIV?

How do ARTs affect body composition in children living with HIV?

SG experts form CKD-aP guidelines for local practice

SG experts form CKD-aP guidelines for local practice

Immunosuppressant use among RA patients may protect against Alzheimer's disease

Immunosuppressant use among RA patients may protect against Alzheimer's disease

Higher-dose methimazole helps GD patients with severe thyrotoxicosis reach euthyroid status

Higher-dose methimazole helps GD patients with severe thyrotoxicosis reach euthyroid status

Puberty blockers ease mood disorders, suicidal thoughts in transgender youths

Puberty blockers ease mood disorders, suicidal thoughts in transgender youths

5-unit IV insulin prevents hypoglycaemia, reduces potassium in adults with hyperkalaemia

5-unit IV insulin prevents hypoglycaemia, reduces potassium in adults with hyperkalaemia