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Phenobarbital (PHB) may be used if patients remain in uncontrolled alcohol withdrawal syndrome (AWS) following treatment with benzodiazepines (BZD), suggests a study.

Phenobarbital use after BZD safe, effective for alcohol withdrawal

Adjunctive dexamethasone lowers death risk in hospitalized children with pneumococcal meningitis

In the treatment of children hospitalized with pneumococcal meningitis, administering dexamethasone within 12 hours of initiating antibiotics appears reduce the 30-day risk of death, according to a retrospective study.

Adjunctive dexamethasone lowers death risk in hospitalized children with pneumococcal meningitis

Chloride level, age linked to AKI development in TBI patients on hypertonic saline

30 Mar 2025

Age and chloride level tend to contribute to the development of acute kidney injury (AKI) in traumatic brain injury (TBI) patients treated with hypertonic saline (HTS), a study has shown.

Chloride level, age linked to AKI development in TBI patients on hypertonic saline

30 Mar 2025

Triptans more effective than NSAID, acetaminophen for acute migraine

The use of triptans and combinations of this drug appears to be better than NSAIDs and acetaminophen alone in relieving pain among individuals with acute attacks of episodic migraine, reports a study.

Triptans more effective than NSAID, acetaminophen for acute migraine

Lebrikizumab relieves itch, skin pain in AD patients previously on dupilumab

28 Mar 2025 bởi

The use of lebrikizumab improves the symptoms of moderate-to-severe atopic dermatitis (AD) in patients previously treated with dupilumab, reports a study presented at AAD 2025.

Lebrikizumab relieves itch, skin pain in AD patients previously on dupilumab

28 Mar 2025

IBD patients at increased risk of intrahepatic cholestasis of pregnancy

Pregnant women with inflammatory bowel disease (IBD), especially those with thiopurine exposure, face a heightened risk of intrahepatic cholestasis of pregnancy (ICP), according to the results of a systematic review and meta-analysis.

IBD patients at increased risk of intrahepatic cholestasis of pregnancy

Remibrutinib improves sleep, daily activities in patients with CSU

28 Mar 2025 bởi

Treatment with remibrutinib, an oral, highly selective Bruton’s tyrosine kinase inhibitor, improved sleep and daily activities in patients with chronic spontaneous urticaria (CSU), according to two phase III REMIX-1 and -2 studies presented at AAD 2025.

Remibrutinib improves sleep, daily activities in patients with CSU

Sacubitril-valsartan a boon to hypertension patients with ESKD on dialysis

Treatment with sacubitril-valsartan (SV) demonstrates good tolerability and may provide some benefits to hypertension patients with end-stage kidney disease (ESKD) who are undergoing dialysis, as shown by the results of a recent meta-analysis.

Sacubitril-valsartan a boon to hypertension patients with ESKD on dialysis

Apremilast boasts long-term improvement in PPP

27 Mar 2025 bởi

Patients with palmoplantar pustulosis (PPP) treated with apremilast show improvements at week 16, with continued treatment resulting in maintained or further improvement at week 52, according to a study presented at AAD 2025. No new safety concerns have been observed.

Apremilast boasts long-term improvement in PPP

Donepezil does little to improve post–COVID-19 fatigue, psychological symptoms

Treatment with the acetylcholinesterase inhibitor donepezil hydrochloride falls short of improving post–COVID-19 conditions such as fatigue and psychological symptoms, as shown in a study from Japan.

Donepezil does little to improve post–COVID-19 fatigue, psychological symptoms