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AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations
The combination of niraparib (NIRA) and abiraterone acetate plus prednisone (AAP) results in significant improvements in radiographic progression-free survival (rPFS) and time to symptomatic progression (TSP) in metastatic castration-sensitive prostate cancer (mCSPC) patients with alterations in homologous recombination repair (HRR) genes, as shown by the results of the phase III AMPLITUDE trial.
AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations
một ngày trước
Gemcitabine for IR-NMIBC tied to more recurrence vs BCG
Treatment-naive patients with immediate-risk (IR) nonmuscle-invasive bladder cancer (NMIBC) who received gemcitabine appear to have greater recurrence risk than those given Bacillus Calmette-Guerin (BCG). Both treatments, however, are effective against disease progression.
Gemcitabine for IR-NMIBC tied to more recurrence vs BCG
06 Jun 2025
Nerve-sparing technique preserves erectile function after RARP
A nerve-sparing technique decreases erectile dysfunction in men undergoing robot-assisted radical prostatectomy (RARP) for prostate cancer in a phase III study.