Molecular structure pattern

Osteoporosis Differential Diagnosis

Last updated: 29 September 2025

Differential Diagnosis

Fractures that may be caused by the following should be ruled out:

  • Fibrous dysplasia
  • Infection
  • Osteomalacia
  • Osteonecrosis
  • Paget’s disease
  • Primary or metastatic cancer

Decreased bone density caused by the following should also be ruled out:

  • Cancer therapy
  • Chronic renal and liver disease
  • Drugs
  • Hyperparathyroidism
  • Renal calcium leak
  • Thyroid disease
  • Vitamin D deficiency