News &amp; Updates

Among children with cystic fibrosis, those who contract methicillin-resistant Staphylococcus aureus (MRSA) infection appear to have worse respiratory outcomes, including increased antibiotic exposure and breathing obstruction, as reported in a retrospective study.

MRSA infection may be detrimental to children with cystic fibrosis

From flare-ups to freedom: Real-world applications of upadacitinib in difficult-to-treat atopic dermatitis

In this article, Dr Marco Ho discusses the applications of upadacitinib in managing severe, difficult-to-treat atopic dermatitis. Dr Ho emphasises the existing unmet need in Hong Kong, particularly in the head and neck region, and reviews recent clinical data and patient cases, highlighting the various benefits upadacitinib can offer.

From flare-ups to freedom: Real-world applications of upadacitinib in difficult-to-treat atopic dermatitis

Interplay between surgery and pharmacotherapy in multimodality treatment of NSCLC

25 Apr 2025 by

At the 28^th Congress of the Asian Pacific Society of Respirology, Dr Alan Sihoe, Consultant in Cardio-Thoracic Surgery, CUHK Medical Centre, Hong Kong, discussed the interplay between pharmacotherapy and surgery in treatment of non-small-cell lung cancer (NSCLC), and emphasized the importance of immunotherapy (IO) timing for maximizing curative surgery rates. Dr Sihoe also shared a case of a patient with stage IVA NSCLC who received surgery in 2017 followed by two lines of tyrosine kinase inhibitor (TKI) treatment and remained well as of November 2024.

Interplay between surgery and pharmacotherapy in multimodality treatment of NSCLC

Certain young stroke survivors can’t get back to work despite recovery

Even as most young people survive ischaemic stroke and achieve functional recovery, only six out of 10 are able to resume work, as shown in a study from Singapore.

Certain young stroke survivors can’t get back to work despite recovery

24 Apr 2025

Psychosocial stress linked to puberty timing

Chronic psychosocial stress (PS) appears to contribute to the delayed onset of pubertal signs in children, suggests a recent study.

Psychosocial stress linked to puberty timing

Statin alone ‘insufficient’ in meeting LDL-C targets in patients with IHD

Significant treatment gaps persist in lipid management among individuals at very high cardiovascular risk, with up to 80 percent of patients not achieving their low-density lipoprotein cholesterol (LDL-C) goals, reports a Singapore study.

Statin alone ‘insufficient’ in meeting LDL-C targets in patients with IHD

Primary aldosteronism prevalent in PTC patients with hypertension

Papillary thyroid cancer (PTC) in individuals with arterial hypertension is independently associated with a diagnosis of primary aldosteronism (PA), reports a study.

Primary aldosteronism prevalent in PTC patients with hypertension

Novel urine test shows promise for kidney cancer recurrence surveillance

The urine GAGome score appears to be a promising biomarker for detecting clear cell renal cell carcinoma (ccRCC) recurrence, findings from the AURORAX-0087A trial suggest.

Novel urine test shows promise for kidney cancer recurrence surveillance

Add-on metformin of little benefit in advanced stage ovarian cancer

Using metformin in addition to first-line platinum/taxane-based chemotherapy does not appear to produce survival gains in patients with newly diagnosed advanced stage ovarian cancer, according to a study.

Add-on metformin of little benefit in advanced stage ovarian cancer

Pacemaker implantation after TAVI linked to long-term poor outcomes

Pacemaker implantation after transcatheter aortic valve implantation (TAVI) was associated with a significantly worse prognosis in terms of all-cause and cardiovascular (CV) mortality, according to the SwissTAVI trial presented at EHRA 2025.

Pacemaker implantation after TAVI linked to long-term poor outcomes