Ramadan fasting ups risk of dyspeptic symptoms in women, older adults

Ramadan fasting may induce dyspeptic symptoms, especially in women and older adults, suggests a study. Medication timing and dietary changes during fasting appear to influence such risk.

The prevalence of dyspepsia was greater in females than males (32 percent vs 23 percent), with a higher proportion of nonfasting women among dyspeptic patients. Likewise, dyspepsia prevalence was increased in older patients (>65 years; p=0.026).

Notably, individuals who fast during Ramadan were 2.1 times more likely to experience dyspeptic symptoms. Fasting patients had lower use of NSAIDs, but no significant association with dyspepsia was observed (p=0.139).

“Highlighting the importance of the pre-dawn meal (Suhoor) in managing dyspeptic symptoms is essential,” the authors said. “Tailored guidance should be provided to individuals at higher risk during Ramadan.”

This cohort study included 1,258 clinic patients, with 150 meeting the eligibility criteria. Dyspepsia was diagnosed using the Rome IV criteria, and fasting hours were taken into consideration. The authors then analysed the associations between dyspepsia and fasting, NSAID use, and demographics.

“Dyspepsia, a common gastrointestinal issue characterized by upper abdominal discomfort, can be influenced by diet, medication, and lifestyle changes,” the authors said.

“Ramadan fasting involves refraining from food and drink from dawn to sunset, affecting various physiological processes, including digestion. The fasting period can range from 12 to 18 hours depending on the year, potentially impacting the prevalence of dyspeptic symptoms,” they added.