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Icosabutate shows potential as treatment for MASH

Treatment with icosabutate is associated with encouraging fibrosis and noninvasive biomarker data, lending support for its development in patients with metabolic dysfunction-associated steatohepatitis (MASH), reports a study.

Icosabutate shows potential as treatment for MASH

1 hour ago

RA patients at high risk of degenerative valvular heart disease

7 hours ago

Rheumatoid arthritis (RA) may be associated with an increased risk of new-onset degenerative aortic stenosis, aortic regurgitation, and mitral regurgitation, as suggested in a study.

RA patients at high risk of degenerative valvular heart disease

7 hours ago

Curcumin in curry may boost brain health

23 hours ago by

Dietary curcumin consumption through curry is good for the brain, being associated with a reduced risk of mild cognitive impairment or dementia in older Singaporeans, as shown in a study.

Curcumin in curry may boost brain health

23 hours ago

Bile acid accumulation predicts liver injury after portoenterostomy

a day ago

The accumulation of altered serum bile acids appears to increase the risk of liver disease progression and result in poorer transplant-free survival following Kasai portoenterostomy (KPE) for biliary atresia (BA), a study has shown.

Bile acid accumulation predicts liver injury after portoenterostomy

a day ago

First-line antiseizure medications equally effective in routine paediatric care

a day ago

In the first-line treatment of newly diagnosed childhood epilepsy, antiseizure medications (ASMs) such as oxcarbazepine, valproate, levetiracetam, topiramate, and lamotrigine perform similarly, with no notable difference in outcomes, according to a retrospective cohort study.

First-line antiseizure medications equally effective in routine paediatric care

a day ago

Navepegritide tied to increased growth velocity in children with ACH

a day ago by

Once-weekly treatment with navepegritide was associated with significantly improved annualized growth velocity (AGV) in children with achondroplasia (ACH) compared with placebo, according to results from the pivotal ApproaCH trial presented at ENDO 2025.

Navepegritide tied to increased growth velocity in children with ACH

a day ago

Several factors tied to treatment failure in children starting first-line ART

a day ago by

In children living with HIV initiating antiretroviral therapy (ART), factors such as the ART regimen, age, BMI, and baseline CD4 count, among others, can predict treatment failure, according to a study.

Several factors tied to treatment failure in children starting first-line ART

a day ago

Third-line secukinumab tied to reduced survival in axSpA, axPsA

22 Aug 2025 by

A real-word study in Argentina has found poor access to secukinumab treatment among patients with public health insurance than those using the social security system or private health coverage. Furthermore, use of secukinumab as third-line therapy or higher is associated with less survival.

Third-line secukinumab tied to reduced survival in axSpA, axPsA

22 Aug 2025

$Vedolizumab–tofacitinib combo induces response in refractory UC$

Vedolizumab–tofacitinib combo induces response in refractory UC

22 Aug 2025

Patients with ulcerative colitis (UC) refractory to anti-TNF and second-line therapies appear to benefit from combination therapy with vedolizumab plus tofacitinib, with many of them achieving clinical remission, as shown in a study.

Vedolizumab–tofacitinib combo induces response in refractory UC

22 Aug 2025

Lung nodule surveillance programme helps detect early-stage lung cancer

22 Aug 2025 by

A lung nodule surveillance programme at Queen Mary Hospital (QMH) facilitates diagnosis of early-stage lung cancer. Data from the programme’s first year of implementation showed a higher proportion of early-stage lung cancer diagnoses compared with the Hong Kong Cancer Registry’s (HKCR) annual report.

Lung nodule surveillance programme helps detect early-stage lung cancer

22 Aug 2025

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Icosabutate shows potential as treatment for MASH

Icosabutate shows potential as treatment for MASH

RA patients at high risk of degenerative valvular heart disease

RA patients at high risk of degenerative valvular heart disease

Curcumin in curry may boost brain health

Curcumin in curry may boost brain health

Bile acid accumulation predicts liver injury after portoenterostomy

Bile acid accumulation predicts liver injury after portoenterostomy

First-line antiseizure medications equally effective in routine paediatric care

First-line antiseizure medications equally effective in routine paediatric care

Navepegritide tied to increased growth velocity in children with ACH

Navepegritide tied to increased growth velocity in children with ACH

Several factors tied to treatment failure in children starting first-line ART

Several factors tied to treatment failure in children starting first-line ART

Third-line secukinumab tied to reduced survival in axSpA, axPsA

Third-line secukinumab tied to reduced survival in axSpA, axPsA

Vedolizumab–tofacitinib combo induces response in refractory UC

Vedolizumab–tofacitinib combo induces response in refractory UC

Lung nodule surveillance programme helps detect early-stage lung cancer

Lung nodule surveillance programme helps detect early-stage lung cancer