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Old drug, new purpose: Low-dose ATG may halt T1D progression in youths

The old immunomodulatory drug antithymocyte globulin (ATG), administered at a low dose, can safely reduce the loss of beta-cell function in young people with recent-onset type 1 diabetes (T1D), as shown in the phase II MELD-ATG trial.

Old drug, new purpose: Low-dose ATG may halt T1D progression in youths

11 hours ago

Liver-directed RT plus atezolizumab-bevacizumab improves response rates in HCC patients

12 hours ago

Adding liver-directed radiation therapy (RT) to atezolizumab and bevacizumab (A/B) produces limited additional toxicity with higher response rates among patients with hepatocellular carcinoma (HCC), reports a recent study. However, substantial differences in baseline characteristics hinder a full interpretation of this data.

Liver-directed RT plus atezolizumab-bevacizumab improves response rates in HCC patients

12 hours ago

Engaging in physical activity may prevent MACE, death in people with T2D

13 hours ago by

An inverse association exists between self-reported physical activity (PA) and the risk of major adverse cardiac events (MACE) and all-cause mortality among individuals with type 2 diabetes (T2D) and no previous cardiovascular disease (CVD), suggests a study presented at EASD 2025.

Engaging in physical activity may prevent MACE, death in people with T2D

13 hours ago

Childhood ALL burden drops but inequalities persist

14 hours ago

The global burden of childhood acute lymphoblastic leukemia (ALL) has gradually decreased, with steady improvements in quality of care, but inequalities remain a significant challenge, according to a study.

Childhood ALL burden drops but inequalities persist

14 hours ago

OSA rates up on weekends

15 hours ago by

The incidence of obstructive sleep apnoea (OSA) is higher on weekends than on weekdays, a study reports.

OSA rates up on weekends

15 hours ago

Antioxidant supplementation in men seeking fertility care does not improve pregnancy rates

19 hours ago

The use of antioxidant supplements in men seeking fertility care does not appear to increase the chances of conceiving for their female partners, as shown in the multicentre SUMMER trial.

Antioxidant supplementation in men seeking fertility care does not improve pregnancy rates

19 hours ago

CBT for insomnia improves sleep outcomes in patients with chronic disease

a day ago by

Cognitive behavioural therapy (CBT) for insomnia (CBT-I) helps reduce its severity and improve other sleep outcomes in patients with chronic disease, such as chronic pain, cardiovascular disease, and cancer, according to the results of a meta-analysis.

CBT for insomnia improves sleep outcomes in patients with chronic disease

a day ago

Infliximab superior to adalimumab in bio-naïve patients with FCD

a day ago

A recent study has shown infliximab’s superiority over adalimumab in the treatment of bio-naïve patients with fistulizing Crohn’s disease (FCD). However, there is no therapeutic difference seen in bio-exposed FCD.

Infliximab superior to adalimumab in bio-naïve patients with FCD

a day ago

Transcutaneous auricular VNS eases constipation, pain in IBS-C

a day ago by

The use of transcutaneous auricular vagus nerve stimulation (taVNS) is effective in improving constipation and abdominal pain, as well as anxiety and depression, in patients with constipation-predominant irritable bowel syndrome (IBS-C), reports a study.

Transcutaneous auricular VNS eases constipation, pain in IBS-C

a day ago

Oxidative balance score inversely linked to advanced CKM risk

a day ago

Higher levels of oxidative balance score (OBS) are associated with a lower risk of advanced cardiovascular‒kidney‒metabolic (CKM) syndrome, reveals a study.

Oxidative balance score inversely linked to advanced CKM risk

a day ago

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Old drug, new purpose: Low-dose ATG may halt T1D progression in youths

Old drug, new purpose: Low-dose ATG may halt T1D progression in youths

Liver-directed RT plus atezolizumab-bevacizumab improves response rates in HCC patients

Liver-directed RT plus atezolizumab-bevacizumab improves response rates in HCC patients

Engaging in physical activity may prevent MACE, death in people with T2D

Engaging in physical activity may prevent MACE, death in people with T2D

Childhood ALL burden drops but inequalities persist

Childhood ALL burden drops but inequalities persist

OSA rates up on weekends

OSA rates up on weekends

Antioxidant supplementation in men seeking fertility care does not improve pregnancy rates

Antioxidant supplementation in men seeking fertility care does not improve pregnancy rates

CBT for insomnia improves sleep outcomes in patients with chronic disease

CBT for insomnia improves sleep outcomes in patients with chronic disease

Infliximab superior to adalimumab in bio-naïve patients with FCD

Infliximab superior to adalimumab in bio-naïve patients with FCD

Transcutaneous auricular VNS eases constipation, pain in IBS-C

Transcutaneous auricular VNS eases constipation, pain in IBS-C

Oxidative balance score inversely linked to advanced CKM risk

Oxidative balance score inversely linked to advanced CKM risk