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GLP-1RA, DPP-4i do not prevent COVID-19 but reduce hospitalization risk in infected patients

New research suggests that in older adults with type 2 diabetes (T2D) who are taking metformin, using dipeptidyl peptidase-4 inhibitors (DPP4is) and glucagon-like peptide-1 receptor agonists (GLP1RAs) has a null effect on the risk of COVID-19 infection. However, among those who do contract the virus, the use of these drugs appears to lower the risk of hospitalization.

GLP-1RA, DPP-4i do not prevent COVID-19 but reduce hospitalization risk in infected patients

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Frailty common in patients with vasculitis

1 hour ago

Frailty appears to be a familiar feature among patients with multiple forms of vasculitis, suggesting a substantial subset of patients at risk for worse outcomes, suggests a study.

Frailty common in patients with vasculitis

1 hour ago

Personalized approach may improve PrEP uptake in MSM, transgenders

2 hours ago by

A recent study in the Philippines has identified key demographic and behavioural patterns among Filipino men who have sex with men (MSM) and transgender individuals (TGIs) regarding their awareness of pre-exposure prophylaxis (PrEP) and modality preferences.

Personalized approach may improve PrEP uptake in MSM, transgenders

2 hours ago

Longer lactation duration tied to lower maternal CAD, stroke risks

3 hours ago

Extended durations of lactation appear to reduce the risk of maternal coronary artery disease (CAD) diagnosed before age 70 years, according to a study.

Longer lactation duration tied to lower maternal CAD, stroke risks

3 hours ago

Hormone therapy use has no bearing on severe COVID-19 outcomes

20 hours ago

A recent study suggests that the use of hormone therapy does not contribute to increased women with severe symptoms of COVID-19.

Hormone therapy use has no bearing on severe COVID-19 outcomes

20 hours ago

Intermittent energy restriction stands out for improving outcomes in people with T2D, obesity

a day ago by

In individuals with type 2 diabetes (T2D) and obesity, an intermittent energy restriction (IER) diet helps with glucose control, with the advantage of improving insulin sensitivity, reducing triglycerides, and being easier to follow compared with other dietary interventions, as shown in a single-centre randomized controlled trial.

Intermittent energy restriction stands out for improving outcomes in people with T2D, obesity

a day ago

Dapagliflozin plus spironolactone improves outcomes in HFpEF

a day ago

Combined treatment with dapagliflozin and spironolactone results in greater reductions in N-terminal pro–B-type natriuretic peptide (NT-proBNP) than dapagliflozine alone in patients with heart failure with preserved ejection fraction (HFpEF), a recent study has shown.

Dapagliflozin plus spironolactone improves outcomes in HFpEF

a day ago

Unhealthy weight in parents before pregnancy tied to adverse birth outcomes

a day ago

The preconception weight of parents, whether too low or too high, contributes to the risk of adverse birth outcomes, including perinatal death and birth defects, according to a study.

Unhealthy weight in parents before pregnancy tied to adverse birth outcomes

a day ago

Hypertension in pregnancy may be a risk factor for Alzheimer’s disease in Asians

16 Aug 2025 by

Women with a history of hypertensive disorders in pregnancy are at increased risk of developing brain changes that lead to Alzheimer’s disease (AD), according to a study from Singapore.

Hypertension in pregnancy may be a risk factor for Alzheimer’s disease in Asians

16 Aug 2025

Switching to DOACs may prevent stroke, bleeding in older adults

16 Aug 2025

Older patients on a vitamin K antagonist (VKA) derive benefits from switching to standard-dose (SD) direct-acting oral anticoagulant (DOAC) as shown by significant decreases in stroke or systemic embolism, fatal and intracranial bleeding, and death, reveals a study.

Switching to DOACs may prevent stroke, bleeding in older adults

16 Aug 2025

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GLP-1RA, DPP-4i do not prevent COVID-19 but reduce hospitalization risk in infected patients

GLP-1RA, DPP-4i do not prevent COVID-19 but reduce hospitalization risk in infected patients

Frailty common in patients with vasculitis

Frailty common in patients with vasculitis

Personalized approach may improve PrEP uptake in MSM, transgenders

Personalized approach may improve PrEP uptake in MSM, transgenders

Longer lactation duration tied to lower maternal CAD, stroke risks

Longer lactation duration tied to lower maternal CAD, stroke risks

Hormone therapy use has no bearing on severe COVID-19 outcomes

Hormone therapy use has no bearing on severe COVID-19 outcomes

Intermittent energy restriction stands out for improving outcomes in people with T2D, obesity

Intermittent energy restriction stands out for improving outcomes in people with T2D, obesity

Dapagliflozin plus spironolactone improves outcomes in HFpEF

Dapagliflozin plus spironolactone improves outcomes in HFpEF

Unhealthy weight in parents before pregnancy tied to adverse birth outcomes

Unhealthy weight in parents before pregnancy tied to adverse birth outcomes

Hypertension in pregnancy may be a risk factor for Alzheimer’s disease in Asians

Hypertension in pregnancy may be a risk factor for Alzheimer’s disease in Asians

Switching to DOACs may prevent stroke, bleeding in older adults

Switching to DOACs may prevent stroke, bleeding in older adults