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Nortriptyline misses mark in functional dyspepsia trial

The tricyclic antidepressant nortriptyline is only as good as placebo in terms of reducing symptoms of functional dyspepsia in preselected patients, according to the results of a multicentre randomized controlled trial.

Nortriptyline misses mark in functional dyspepsia trial

1 hour ago

Low SBP does not raise risk of all-cause mortality, CV events

7 hours ago

Blood pressure (BP) shows a linear association with several cardiovascular (CV) and renal outcomes in patients with type 2 diabetes (T2D), reveals a study.

Low SBP does not raise risk of all-cause mortality, CV events

7 hours ago

PFS gains seen with savolitinib–osimertinib combo in EGFR-mutant, MET-amplified NSCLC

13 hours ago

Treatment with the combination of savolitinib plus osimertinib prolongs progression-free survival (PFS) in patients with non-small cell lung cancer (NSCLC) harbouring EGFR mutation and MET amplification, as shown in the phase III SACHI trial.

PFS gains seen with savolitinib–osimertinib combo in EGFR-mutant, MET-amplified NSCLC

13 hours ago

Age, rehabilitation timing factor in functional outcomes in stroke survivors

a day ago by

Older age and early initiation of rehabilitation predict functional improvement in patients undergoing stroke rehabilitation within Singapore’s community hospital setting, according to local research.

Age, rehabilitation timing factor in functional outcomes in stroke survivors

a day ago

CAD incidence lower in HCM vs non-HCM patients

a day ago

Patients with hypertrophic cardiomyopathy (HCM) undergoing computed tomography angiography (CTA) for table chest pain enjoy a lower incidence of obstructive coronary artery disease (CAD) and show more stable coronary plaque features than those with no HCM, reveals a study.

CAD incidence lower in HCM vs non-HCM patients

a day ago

Delayed puberty in males a red flag for T2D risk

a day ago

Male teens with delayed puberty have an increased likelihood of developing type 2 diabetes (T2D) in early adulthood, regardless of BMI, according to a retrospective study.

Delayed puberty in males a red flag for T2D risk

a day ago

GLP-1RA bests aspirin for CRC prevention

06 Feb 2026 by

Use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) appears to confer greater protection against the development of colorectal cancer (CRC) as compared with aspirin, according to a retrospective study.

GLP-1RA bests aspirin for CRC prevention

06 Feb 2026

High PUFA slightly better than high MUFA diets in lowering blood lipids

06 Feb 2026

Diets high in polyunsaturated fatty acid (PUFA) demonstrate slightly greater benefits over high monounsaturated fatty acid (MUFA) diets in reducing blood lipids, reports a study.

High PUFA slightly better than high MUFA diets in lowering blood lipids

06 Feb 2026

Zanidatamab outdoes trastuzumab as first-line treatment of HER2-positive mGEA

06 Feb 2026 by

Treatment with zanidatamab combined with tislelizumab and/or chemotherapy (CT) significantly improves progression-free survival (PFS) in patients with HER2-positive locally advanced, unresectable, or metastatic gastroesophageal adenocarcinoma (mGEA), as shown in the primary analysis from HERIZON-GEA-01.

Zanidatamab outdoes trastuzumab as first-line treatment of HER2-positive mGEA

06 Feb 2026

Delays in hypertension diagnosis persist despite records of high BP measurement

06 Feb 2026

A recent study has observed delays in hypertension diagnosis, which potentially results in hospital visits and other cardiovascular diagnoses.

Delays in hypertension diagnosis persist despite records of high BP measurement

06 Feb 2026

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Nortriptyline misses mark in functional dyspepsia trial

Nortriptyline misses mark in functional dyspepsia trial

Low SBP does not raise risk of all-cause mortality, CV events

Low SBP does not raise risk of all-cause mortality, CV events

PFS gains seen with savolitinib–osimertinib combo in EGFR-mutant, MET-amplified NSCLC

PFS gains seen with savolitinib–osimertinib combo in EGFR-mutant, MET-amplified NSCLC

Age, rehabilitation timing factor in functional outcomes in stroke survivors

Age, rehabilitation timing factor in functional outcomes in stroke survivors

CAD incidence lower in HCM vs non-HCM patients

CAD incidence lower in HCM vs non-HCM patients

Delayed puberty in males a red flag for T2D risk

Delayed puberty in males a red flag for T2D risk

GLP-1RA bests aspirin for CRC prevention

GLP-1RA bests aspirin for CRC prevention

High PUFA slightly better than high MUFA diets in lowering blood lipids

High PUFA slightly better than high MUFA diets in lowering blood lipids

Zanidatamab outdoes trastuzumab as first-line treatment of HER2-positive mGEA

Zanidatamab outdoes trastuzumab as first-line treatment of HER2-positive mGEA

Delays in hypertension diagnosis persist despite records of high BP measurement

Delays in hypertension diagnosis persist despite records of high BP measurement