News & Updates

First-line benmelstobart–anlotinib combo yields PFS gain in advanced PD-L1-positive NSCLC

In the first-line treatment of patients with advanced PD-L1–positive non–small cell lung cancer (NSCLC), the combination of the anti-PD-L1 monoclonal antibody benmelstobart plus the multikinase inhibitor anlotinib prolongs progression-free survival (PFS) compared with pembrolizumab monotherapy, according to the phase III CAMPASS study conducted in China.

First-line benmelstobart–anlotinib combo yields PFS gain in advanced PD-L1-positive NSCLC

14 hours ago

Wildfire smoke exposure ups risk of heart failure in older adults

15 hours ago

Exposure to wildfire smoke for an extended period may increase the risk of heart failure (HF) in older adults, particularly women and socially vulnerable populations, suggests a study.

Wildfire smoke exposure ups risk of heart failure in older adults

15 hours ago

White coat hypertension prevalent in people with elevated clinic BP

16 hours ago by

More than half of individuals with elevated clinic blood pressure (BP) attending a primary care clinic in Singapore have either white coat hypertension (WCH) or undiagnosed hypertension, reports a study.

White coat hypertension prevalent in people with elevated clinic BP

16 hours ago

Psilocybin eases depression, with minor impact on brain responsiveness

17 hours ago

Treatment with psilocybin results in significant improvements in depressive symptoms, and its use only shows a minor effect on brain responsiveness to emotional stimuli.

Psilocybin eases depression, with minor impact on brain responsiveness

17 hours ago

Utidelone plus bevacizumab shows promise in ERBB2-negative MBC

22 hours ago

Combination treatment with utidelone plus bevacizumab has demonstrated therapeutic potential in patients with ERBB2-negative metastatic breast cancer (MBC) and active brain metastases in a single-arm, phase II study conducted in China.

Utidelone plus bevacizumab shows promise in ERBB2-negative MBC

22 hours ago

Undernutrition drives up hospitalizations for older Singaporeans

a day ago by

New research points to undernutrition as a key factor contributing to increases in emergency department (ED) visits and inpatient admissions among older adults in Singapore.

Undernutrition drives up hospitalizations for older Singaporeans

a day ago

Short-course antibiotic for paediatric CAP on par with long-course regimen

a day ago

A short-course antibiotic treatment for children with community-acquired pneumonia (CAP) demonstrates effectiveness similar to the long-course regimen but with fewer serious adverse events (AEs), reports a study.

Short-course antibiotic for paediatric CAP on par with long-course regimen

a day ago

AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations

a day ago by

The combination of niraparib (NIRA) and abiraterone acetate plus prednisone (AAP) results in significant improvements in radiographic progression-free survival (rPFS) and time to symptomatic progression (TSP) in metastatic castration-sensitive prostate cancer (mCSPC) patients with alterations in homologous recombination repair (HRR) genes, as shown by the results of the phase III AMPLITUDE trial.

AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations

a day ago

Ceftazidime-avibactam, ceftolozane-tazobactam safe for use in children

a day ago

Treatment with either ceftazidime-avibactam (CAZ/AVI) or ceftolozane-tazobactam (C/T) is well tolerated and effective in children infected with Gram-negative pathogens resistant to carbapenems, a recent study has shown.

Ceftazidime-avibactam, ceftolozane-tazobactam safe for use in children

a day ago

Flu shot during pregnancy extends protection to offspring

a day ago

Influenza vaccination in pregnant women, especially during the second or third trimester, cuts the risk of infection in infants, as shown in a study.

Flu shot during pregnancy extends protection to offspring

a day ago

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First-line benmelstobart–anlotinib combo yields PFS gain in advanced PD-L1-positive NSCLC

First-line benmelstobart–anlotinib combo yields PFS gain in advanced PD-L1-positive NSCLC

Wildfire smoke exposure ups risk of heart failure in older adults

Wildfire smoke exposure ups risk of heart failure in older adults

White coat hypertension prevalent in people with elevated clinic BP

White coat hypertension prevalent in people with elevated clinic BP

Psilocybin eases depression, with minor impact on brain responsiveness

Psilocybin eases depression, with minor impact on brain responsiveness

Utidelone plus bevacizumab shows promise in ERBB2-negative MBC

Utidelone plus bevacizumab shows promise in ERBB2-negative MBC

Undernutrition drives up hospitalizations for older Singaporeans

Undernutrition drives up hospitalizations for older Singaporeans

Short-course antibiotic for paediatric CAP on par with long-course regimen

Short-course antibiotic for paediatric CAP on par with long-course regimen

AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations

AMPLITUDE: Niraparib plus AAP improves survival in mCSPC patients with gene mutations

Ceftazidime-avibactam, ceftolozane-tazobactam safe for use in children

Ceftazidime-avibactam, ceftolozane-tazobactam safe for use in children

Flu shot during pregnancy extends protection to offspring

Flu shot during pregnancy extends protection to offspring