Abbreviated DAPT strategy in an NSTE-ACS patient
25 Oct 2024
byDr. Tsz-Ki Lau, Specialist in Cardiology, United Christian Hospital, Hong Kong
A 70-year-old man presented to our hospital in April 2023 with intermittent chest pain and shortness of breath of 7 days’ duration. He was a smoker with multiple comorbidities, including hypertension, diabetes mellitus (DM), hyperlipidaemia, ischaemic heart disease and history of peptic ulcer, for which he was receiving amlodipine 5 mg QD, metformin 500 mg BID, atorvastatin 40 mg QD, aspirin 80 mg QD, and pantoprazole 40 mg QD, respectively. He had a CT coronary angiogram in 2018 and it showed mild stenosis in the left anterior descending (LAD) artery, which was managed with aspirin 80 mg QD. The patient developed a haemorrhagic peptic ulcer associated with aspirin use in June 2021. After stabilizing the condition with pantoprazole and blood transfusion, a repeated oesophagogastroduodenoscopy (OGD) was performed, showing resolution of the ulcer. Aspirin treatment was continued along with pantoprazole.