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AD trial: Cognitive impairment exacerbated with reduced iron in brain
14 Nov 2024
byJairia Dela Cruz
Brain iron-lowering therapy with deferiprone appears to do more harm than good in patients with Alzheimer's disease (AD), being associated with increased cognitive decline in a phase II study.
AD trial: Cognitive impairment exacerbated with reduced iron in brain
14 Nov 2024
SGLT-2 inhibitors stop kidney stone recurrence in T2D patients with nephrolithiasis, gout
13 Nov 2024
byStephen Padilla
Use of an SGLT-2 inhibitor, compared with a GLP-1 receptor agonist or a DPP-4 inhibitor, helps to prevent nephrolithiasis from recurring in patients with type 2 diabetes (T2D) and pre-existing nephrolithiasis or gout, as shown in target trial emulation studies.
SGLT-2 inhibitors stop kidney stone recurrence in T2D patients with nephrolithiasis, gout
13 Nov 2024
Prompt DOAC therapy after stroke safe for AF patients
11 Nov 2024
byJairia Dela Cruz
Initiating direct oral anticoagulants (DOACs) within 4 days after an ischaemic stroke in patients with atrial fibrillation (AF) is safe and yields similar outcomes as delayed initiation, as shown in the phase 4 OPTIMAS trial.