Peptic Ulcer Disease Tóm tắt về bệnh

Tổng quan

Peptic ulcer disease (PUD) is characterized by mucosal damage secondary to pepsin and gastric acid secretion, as stated in the Introduction section.

The incidence of uncomplicated PUD is approximately 1 case per 1,000 person-years, while the incidence of ulcer complications is approximately 0.7 cases per 1,000 person-years. A detailed discussion about the prevalence of peptic ulcer disease is in the Epidemiology section.

The Pathophysiology section states that ulceration in peptic ulcer disease occurs when a disruption in the integrity and normal processes of the gastric mucosa leads to an imbalance between the stomach's acid production and its protective barrier. The development process in patients with peptic ulcer disease is discussed in this section.

Risk factors such as age, NSAID use, and H pylori infection are explained in the Risk Factors section.

Peptic Ulcer Disease_Disease Summary

History and Physical Examination

The History section describes the clinical and alarm features of patients with peptic ulcer disease. The Physical Examination section explains the signs seen in patients with PUD and its complications.

Chẩn đoán

Discussion on the diagnostic procedures and laboratory tests recommended in the evaluation of peptic ulcer disease is in the Laboratory Tests and Ancillaries section. Imaging studies such as radiologic upper gastrointestinal series and abdominal computed tomography (CT) scan as an option for the diagnosis of peptic ulcer disease and its complications are discussed in the Imaging section.

Other diseases that can present with the same symptoms as peptic ulcer disease are listed in the Differential Diagnosis section.

Xử trí

General therapy principles and management of peptic ulcer disease are in the Principles of Therapy section.

The Pharmacological Therapy section discusses in detail the symptomatic therapy and medication options in the treatment of peptic ulcer disease.

The Nonpharmacological section includes things to educate the patient about the things that may precipitate or aggravate the symptoms and worsen the disease course in patients with peptic ulcer disease.

Indications for surgical intervention in patients with peptic ulcer disease are in the Surgery section.

The Monitoring section identifies the different complications that may be seen in patients with poorly treated peptic ulcer disease.