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Combination treatment with pembrolizumab and adjuvant radiotherapy (RT) does not pose any serious risk to patients with triple-negative breast cancer (TNBC), showing no increase in radiation-related adverse events (AEs), a study has shown.

Is pembrolizumab plus RT safe to administer in TNBC?

Sacituzumab tirumotecan feasible in advanced urothelial carcinoma

Treatment with sacituzumab tirumotecan (sac-TMT) shows a promising antitumour activity and an acceptable safety profile in patients with heavily pretreated advanced or metastatic urothelial carcinoma (UC), according to a phase II study.

Sacituzumab tirumotecan feasible in advanced urothelial carcinoma

Tucatinib-T-DM1 combo improves PFS in patients with metastatic breast cancer

Treatment with trastuzumab emtansine (T-DM1) plus tucatinib safely prolongs progression-free survival (PFS) in patients with previously treated HER2-positive locally advanced (LA) or metastatic breast cancer (MBC), including those with brain metastases, reports a study.

Tucatinib-T-DM1 combo improves PFS in patients with metastatic breast cancer

03 Mar 2026

TENS effectively delivers post-CS pain relief

A prospective quasi-randomized controlled trial presented at SMFM 2026 has demonstrated the potential of transcutaneous electrical nerve stimulation (TENS) to reduce postoperative pain following Caesarean delivery.

TENS effectively delivers post-CS pain relief

Nirsevimab protects against LRTI-related hospitalizations, ED visits in young children

Treatment with nirsevimab helps reduce hospitalizations and emergency department (ED) visits associated with lower respiratory tract infections (LRTIs) in infants and young children, according to the results of a meta-analysis.

Nirsevimab protects against LRTI-related hospitalizations, ED visits in young children

Time-restricted eating lowers BP in paediatric population

Time-restricted eating (TRE) with a 12-hr window, particularly when last meal is completed before 8:00 pm, significantly lowers blood pressure (BP) in children and adolescents with elevated BP compared with a usual eating pattern, according to a recent study.

Time-restricted eating lowers BP in paediatric population

Stopping antidepressants during pregnancy ups risk of mental health emergencies

02 Mar 2026 bởi

Most women on antidepressant therapy discontinue their medications during pregnancy despite guideline recommendations against doing so, and this practice results in more mental health emergencies, according to new research.

Stopping antidepressants during pregnancy ups risk of mental health emergencies

Original New Drug Application Approvals by US FDA (1-15 February 2026)

New drug applications approved by US FDA as of 1-15 February 2026 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (1-15 February 2026)

Does hormone therapy raise risk of IBD flare in gender-diverse adults?

The risk of an inflammatory bowel disease (IBD) flare does not increase in the year after initiating gender-affirming hormone therapy (GAHT), but individuals with IBD prior to hormone start and those receiving testosterone have a higher likelihood of having an IBD flare, a study has shown.

Does hormone therapy raise risk of IBD flare in gender-diverse adults?